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Somatic Cell Hybridization

Fusion of 2 somatic cells to form a heterokaryon.
National Institutes of Health

Papers overview

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Highly Cited
1996
Highly Cited
1996
The idiotype of the Ig expressed by a B-cell malignancy (Id) can serve as a unique tumor-specific antigen and as a model for… 
Highly Cited
1996
Highly Cited
1996
The primary molecular defect underlying Niemann-Pick C disease (NPC) is still unknown. A wide spectrum of clinical and… 
Highly Cited
1996
Highly Cited
1996
Fanconi anaemia (FA) is an autosomal recessive disorder characterized by a diversity of clinical symptoms including skeletal… 
Highly Cited
1995
Highly Cited
1995
The nuclear receptor superfamily of transcription factors, which includes the retinoic acid receptors and v-erb A, play important… 
Highly Cited
1983
Highly Cited
1983
The Epstein-Barr virus (EBV) genome stably persists in latently infected Burkitt tumor cells and growth-transformed B lymphocytes… 
Highly Cited
1978
Highly Cited
1978
Advances in somatic cell hybridization techniques have made it possible to generate hybrid cell lines producing monospecific… 
Highly Cited
1978
Highly Cited
1978
Somatic cell hybrids (hybridomas) between mouse myeloma cells and spleen cells derived from BALB/c mice immunized with… 
Highly Cited
1976
Highly Cited
1976
Modifications in the techniques for the induction of mammalian somatic cell hybridization by polyethylene glycol (PEG) have led… 
Highly Cited
1972
Highly Cited
1972
XERODERMA pigmentosum is an autosomal recessive disease characterized by hypersensitivity of the skin to ultraviolet radiation…