Somatic Cell Hybridization

Fusion of 2 somatic cells to form a heterokaryon.
National Institutes of Health

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Topic mentions per year

1970-2013
0102019702013

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Highly Cited
1996
Highly Cited
1996
The primary molecular defect underlying Niemann-Pick C disease (NPC) is still unknown. A wide spectrum of clinical and… (More)
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Highly Cited
1996
Highly Cited
1996
Fanconi anaemia (FA) is an autosomal recessive disorder characterized by a diversity of clinical symptoms including skeletal… (More)
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Highly Cited
1995
Highly Cited
1995
The nuclear receptor superfamily of transcription factors, which includes the retinoic acid receptors and v-erb A, play important… (More)
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1995
1995
The production and local release of various proteolytic enzymes, either by tumor cells or tumor-associated stromal cells, is… (More)
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Highly Cited
1985
Highly Cited
1985
Using a somatic cell hybridization technique, four murine monoclonal antibodies (three immunoglobulin M and one immunoglobulin G3… (More)
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1985
1985
Glucocorticoid-resistant mutants isolated form the glucocorticoid-sensitive human leukemic cell line CEM-C7 can be divided into… (More)
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Highly Cited
1985
Highly Cited
1985
Expression of a basement membrane collagen-degrading metalloprotease activity (collagenase IV) was studied in a series of murine… (More)
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1978
1978
Somatic cell hybrids (hybridomas) between mouse myeloma cells and spleen cells derived from BALB/c mice immunized with… (More)
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1978
1978
B leukemia cells from four different patients were hybridized with a mouse myeloma cell line with polyethylene glycol as a fusing… (More)
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Highly Cited
1976
Highly Cited
1976
Modifications in the techniques for the induction of mammalian somatic cell hybridization by polyethylene glycol (PEG) have led… (More)
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