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Somatic Cell Hybridization

Fusion of 2 somatic cells to form a heterokaryon.
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
Plant tissue culture techniques have become vitally important for pursuing a wide range of fundamental and applied problems in… Expand
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Highly Cited
1996
Highly Cited
1996
The idiotype of the Ig expressed by a B-cell malignancy (Id) can serve as a unique tumor-specific antigen and as a model for… Expand
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Highly Cited
1996
Highly Cited
1996
The primary molecular defect underlying Niemann-Pick C disease (NPC) is still unknown. A wide spectrum of clinical and… Expand
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Highly Cited
1996
Highly Cited
1996
Fanconi anaemia (FA) is an autosomal recessive disorder characterized by a diversity of clinical symptoms including skeletal… Expand
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Highly Cited
1995
Highly Cited
1995
The nuclear receptor superfamily of transcription factors, which includes the retinoic acid receptors and v-erb A, play important… Expand
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Highly Cited
1995
Highly Cited
1995
The production and local release of various proteolytic enzymes, either by tumor cells or tumor-associated stromal cells, is… Expand
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Highly Cited
1978
Highly Cited
1978
Advances in somatic cell hybridization techniques have made it possible to generate hybrid cell lines producing monospecific… Expand
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Highly Cited
1978
Highly Cited
1978
Somatic cell hybrids (hybridomas) between mouse myeloma cells and spleen cells derived from BALB/c mice immunized with… Expand
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Highly Cited
1976
Highly Cited
1976
Modifications in the techniques for the induction of mammalian somatic cell hybridization by polyethylene glycol (PEG) have led… Expand
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Highly Cited
1972
Highly Cited
1972
XERODERMA pigmentosum is an autosomal recessive disease characterized by hypersensitivity of the skin to ultraviolet radiation… Expand
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