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Soman

Known as: Soman [Chemical/Ingredient], Phosphonofluoridic acid, methyl-, 1,2,2-trimethylpropyl ester, Methylphosphonofluoridate, Pinacolyl 
An organophosphorus compound that inhibits cholinesterase. It causes seizures and has been used as a chemical warfare agent.
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (4)

3,3-dimethyl-2-butyl methylphosphonofluoridatepinacolyl dimethylphosphinatepinacolyl methylphosphonic acidpinacolyl methylphosphonochloridate

Broader (4)

Chemical Warfare AgentsCholinesterase InhibitorsConvulsantsNerve Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
The hypertensive response to soman and its relation to brain acetylcholinesterase inhibition.
Intravenous injection of soman in the rat produced a rapid and dose related increase in blood pressure. The dose response curve… 
2004
2004
Iso-OMPA-induced potentiation of soman toxicity in rat correlates with the inhibition of plasma carboxylesterases
Recently, the question was raised as to why iso-OMPA, generally known as a selective irreversible inhibitor of… 
1998
1998
Quinuclidinium-imidazolium compounds: synthesis, mode of interaction with acetylcholinesterase and effect upon Soman intoxicated mice
Abstract Four compounds were prepared: 3-oxo-1- methylquinuclidinium iodide (I), 2-hydroxyiminomethyl-1,3-dimethylimidazolium… 
1997
1997
Consortium aims to revive sterile-mosquito project
[HYDERABAD, INDIA]A controversial US-funded mosquito-control project in Delhi, which was closed down by the Indian government 20… 
Highly Cited
1994
Highly Cited
1994
Anticonvulsant and antilethal effects of the phencyclidine derivative TCP in soman poisoning.
The protection afforded by TCP (thienylcylohexylpiperidine), a non-competitive blocker of N-methyl-D-aspartate (NMDA) receptors… 
1994
1994
Antiepileptic effects of NBQX against soman-induced seizures.
The ability of NBQX, a potent antagonist of AMPA glutamatergic receptors, to prevent or stop seizures induced by the… 
1985
1985
Flexibility of the molecular forms of acetylcholinesterase measured with steady-state and time-correlated fluorescence polarization spectroscopy.
Steady-state and time-correlated fluorescence polarizations have been examined for selected complexes and covalent conjugates of… 
1984
1984
Isolation, in vitro activity, and acute toxicity in mice of the four stereoisomers of soman.
We report the isolation, on a 0.1- to 2-mg scale, of the four stereoisomers of the nerve agent pinacolyl… 
1984
1984
Stereochemical analysis of the nerve agents soman, sarin, tabun, and VX by proton NMR-spectroscopy with optically active shift reagents
Those anticholinesterases of the organophosphate type which are considered to be potential chemical warfare agents (Franke 1977… 
1976
1976
Effect of atropine upon the cerebrovascular system during soman-induced respiratory depression.
The effect of soman-induced respiratory depression upon cerebral vascular physiology was studied in monkeys. There was a…