Solute Carrier Family 22 Member 3, human

Known as: Organic Cation Transporter 3, Solute Carrier Family 22 Member 3, Solute Carrier Family 22 (Extraneuronal Monoamine Transporter), Member 3 
Solute carrier family 22 member 3 (556 aa, ~61 kDa) is encoded by the human SLC22A3 gene. This protein is involved in mediating membrane potential… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
024619962018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
OBJECTIVES The goals of this study were to determine the role of organic cation transporter 3 (OCT3) in the pharmacological… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2010
2010
The plasma membrane monoamine transporter (PMAT) and organic cation transporter 3 (OCT3) are the two most prominent low-affinity… (More)
  • table 1
  • table 2
Is this relevant?
2010
2010
Activation of the hypothalamic-pituitary-adrenal (HPA) axis is associated with increased extracellular serotonin (5-HT) in limbic… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
The effect of oxaliplatin against colorectal cancer is superior to that of cisplatin, but the molecular mechanism(s) involved is… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • table 1
Is this relevant?
2005
2005
The aim of this study is to investigate the placental transport mechanism of cationic compounds by comparison of the uptake of an… (More)
  • table 1
  • figure 2
  • figure 3
  • figure 1
  • figure 6
Is this relevant?
2003
2003
Agmatine has received considerable attention recently. Available evidence suggests that agmatine functions as a neurotransmitter… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2003
2003
In this study we examined the functional expression of the extraneuronal monoamine transporter (EMT) in normal human astrocytes… (More)
Is this relevant?
2001
2001
Several transmembrane transporters of organic compounds are regulated by phosphorylation/dephosphorylation mechanisms. The aim of… (More)
  • table 1
  • figure 7
  • table 2
Is this relevant?
2001
2001
Monoamine clearance is a combined function of uptake mechanisms in the plasma membrane with intracellular metabolizing enzymes… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1998
Highly Cited
1998
We investigated the transport of cationic neurotoxins and neurotransmitters by the potential-sensitive organic transporter OCT3… (More)
Is this relevant?