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Solute Carrier Family 22 Member 3, human

Known as: Organic Cation Transporter 3, Solute Carrier Family 22 Member 3, Solute Carrier Family 22 (Extraneuronal Monoamine Transporter), Member 3 
Solute carrier family 22 member 3 (556 aa, ~61 kDa) is encoded by the human SLC22A3 gene. This protein is involved in mediating membrane potential… Expand
National Institutes of Health

Papers overview

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2015
2015
Metformin, the most widely prescribed antidiabetic drug, requires transporters to enter tissues involved in its pharmacologic… Expand
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2013
2013
Human organic cation transporter 3 (OCT3 and SLC22A3) mediates the uptake of many important endogenous amines and basic drugs in… Expand
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Highly Cited
2010
Highly Cited
2010
OBJECTIVES The goals of this study were to determine the role of organic cation transporter 3 (OCT3) in the pharmacological… Expand
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Highly Cited
2010
Highly Cited
2010
The plasma membrane monoamine transporter (PMAT) and organic cation transporter 3 (OCT3) are the two most prominent low-affinity… Expand
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2010
2010
Activation of the hypothalamic-pituitary-adrenal (HPA) axis is associated with increased extracellular serotonin (5-HT) in limbic… Expand
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2009
2009
The organic cation transporter 3 (OCT3; synonymous: extraneuronal monoamine transporter, EMT, Slc22a3) encodes an isoform of the… Expand
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Highly Cited
2005
Highly Cited
2005
The aim of this study is to investigate the placental transport mechanism of cationic compounds by comparison of the uptake of an… Expand
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2004
2004
The extraneuronal monoamine transporter plays an important role in the inactivation of monoamine transmitters. A basal… Expand
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2003
2003
In this study we examined the functional expression of the extraneuronal monoamine transporter (EMT) in normal human astrocytes… Expand
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Highly Cited
1998
Highly Cited
1998
We investigated the transport of cationic neurotoxins and neurotransmitters by the potential-sensitive organic transporter OCT3… Expand
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