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Solute Carrier Family 22 Member 3, human

Known as: Organic Cation Transporter 3, Solute Carrier Family 22 Member 3, Solute Carrier Family 22 (Extraneuronal Monoamine Transporter), Member 3 
Solute carrier family 22 member 3 (556 aa, ~61 kDa) is encoded by the human SLC22A3 gene. This protein is involved in mediating membrane potential… 
National Institutes of Health

Related topics

Related topics

13 relations
Cellular MembraneIntegral Membrane ProteinsIonophore activityLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
“Polytox” synthetic cathinone abuse: A potential role for organic cation transporter 3 in combined cathinone-induced efflux
2017
2017
A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3).
2014
2014
5-Hydroxytryptamine–Mediated Neurotransmission Modulates Spontaneous and Vagal-Evoked Glutamate Release in the Nucleus of the Solitary Tract Effect of Uptake Blockade
The effect of blockade of either 5-hydroxytryptamine (5-HT)/serotonin transporter (SERT) with citalopram or the organic cation… 
2012
2012
Genetic susceptibility for coronary heart disease and type 2 diabetes complications.
Type II diabetes (T2D)3 represents a major public health challenge, with the WHO having estimated a current prevalence of 346… 
2005
2005
Intra- and extraneuronal monoamineoxidase-A and -B activities after central axotomy (hemisection) on rats
Hemitransection of the left side of rat brain results in a selective increase (40%) in the activity of MAO-B in the left side… 
2004
2004
Toward a rapidly acting antidepressant: the normetanephrine and extraneuronal monoamine transporter (uptake 2) hypothesis.
OBJECTIVE The authors considered the possible role of the extraneuronal monoamine transporter (uptake 2) in accounting for the… 
2003
2003
The localisation of the extraneuronal monoamine transporter (EMT) in rat brain
The extraneuronal monoamine transporter plays an important role in the inactivation of monoamine transmitters. A basal… 
Review
2003
Review
2003
An update on the extraneuronal monoamine transporter (EMT): characteristics, distribution and regulation.
Biological membranes prevent transmembrane diffusion in the majority of organic molecules that bear net charges at physiological… 
1999
1999
Enhanced Antitumor Activity of SarCNU in Comparison to BCNU in an Extraneuronal Monoamine Transporter Positive Human Glioma Xenograft Model
A novel analogue of nitrosoureas, 2-chloroethyl-3-sarcosinamide-1-nitrosourea (SarCNU), has demonstrated increased anticancer… 
1998
1998
The extraneuronal monoamine transporter exists in human central nervous system glia.
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