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Solute Carrier Family 22 Member 2

Known as: Organic Cation Transporter 2 
Solute carrier family 22 member 2 (555 aa, ~63 kDa) is encoded by the human SLC22A2 gene. This protein is involved in mediating tubular uptake of… 
National Institutes of Health

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15 relations
Cellular MembraneDistal convoluted renal tubule structureIntegral Membrane ProteinsIonophore activity

Papers overview

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2019
2019
Kobe University Repository : Kernel タイトル Tit le Organic cat ion t ransporter 2 and tumor budding as independent prognost ic factors in metastat ic colorectal cancer pat ients t reated with oxaliplat…
Oxaliplatin is currently approved for patients with metastatic colorectal cancer (mCRC). Its uptake and consequent cytotoxicity… 
2013
2013
Transport of asymmetric dimethylarginine (ADMA) by cationic amino acid transporter 2 (CAT2), organic cation transporter 2 (OCT2) and multidrug and toxin extrusion protein 1 (MATE1)
Asymmetric dimethylarginine (ADMA), inhibiting the nitric oxide (NO) synthesis from l-arginine, is a known cardiovascular risk… 
2008
2008
Interactionof Cisplatinwith the HumanOrganic CationTransporter 2
Purpose:Cisplatin is predominantly eliminated in theurine throughactive secretion. As the solute carrier organic cation… 
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