Sodium Stibogluconate

Known as: Estibogluconato sodico, Trisodium 1-{[3-carboxylato-5-(1,2-dihydroxyethyl)-1-hydroxy-2,6,7-trioxa-1lambda(5)-stibabicyclo[2.2.1]hept-1-yl]oxy}-5-(1,2-dihydroxyethyl)-1-oxido-2,6,7-trioxa-1lambda(5)-stibabicyclo[2.2.1]heptane-3-carboxylate nonahydrate, stibogluconate sodium 
Pentavalent antimony (Sb) in differential complex formation with gluconic acid with leishmanicidal and potential antineoplastic activities. The Sb… (More)
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
BACKGROUND Antimonials are the mainstay of visceral leishmaniasis (VL) treatment in Africa. The increasing incidence of human… (More)
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2003
2003
Between April 9 and May 5 2000, an outbreak of fatal cardiotoxicity occurred in Nepal amongst visceral leishmaniasis patients… (More)
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Highly Cited
2001
Highly Cited
2001
Using in vitro protein tyrosine phosphatase (PTPase) assays, we found that sodium stibogluconate, a drug used in treatment of… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVES To assess the efficacy and tolerability of aminosidine compared with sodium stibogluconate for treating visceral… (More)
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1993
1993
In a comparative trial of treatment in southern Sudan, visceral leishmaniasis was diagnosed by the following symptoms: fever for… (More)
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Highly Cited
1992
Highly Cited
1992
To determine the relative efficacy and toxicity of stibogluconate and ketoconazole for the treatment of cutaneous leishmaniasis… (More)
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Highly Cited
1990
Highly Cited
1990
The treatment of leishmaniasis, as currently conducted in Kenya with sodium stibogluconate, is unsatisfactory as it is expensive… (More)
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Highly Cited
1986
Highly Cited
1986
Highly Cited
1986
Liver and serum concentrations of antimony in the mouse have been determined after administration of sodium stibogluconate in the… (More)
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1985
1985
Serial electrocardiograms (ECGs) were obtained during 65 courses of sodium stibogluconate treatment in 59 Kenyan patients with… (More)
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