FAQ

Sodium-Hydrogen Antiporter

Known as: Sodium-Hydrogen Exchanger, Sodium Proton Antiporter, Na(+)-H(+)-Antiporter 
A plasma membrane exchange glycoprotein transporter that functions in intracellular pH regulation, cell volume regulation, and cellular response to… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2018
05010019742018

Related topics

Related topics

19 relations
In BloodProcess of secretionSLC9A1 geneadministration & dosage
(More)

Broader (1)

Membrane Transport Proteins

Narrower (5)

NHE1 AntiporterNHE2 AntiporterSLC9A1 protein, humanSLC9A9 protein, human
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Sodium-Hydrogen Antiporter
physiological aspects
agonists
chemical synthesis
Membrane Transport Proteins
antiporter activity

Papers overview

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Highly Cited
2007
Highly Cited
2007
Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer
Conceptual models of carcinogenesis typically consist of an evolutionary sequence of heritable changes in genes controlling… (More)
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Highly Cited
2005
Highly Cited
2005
Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation.
Four isoforms of the Na+/H+ exchanger (NHE6-NHE9) are distributed to intracellular compartments in human cells. They are… (More)
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Highly Cited
2002
Highly Cited
2002
Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility.
The orphan receptor APJ and its recently identified endogenous ligand, apelin, exhibit high levels of mRNA expression in the… (More)
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Highly Cited
1999
Highly Cited
1999
Vasopressin increases Na-K-2Cl cotransporter expression in thick ascending limb of Henle's loop.
To investigate whether the enhancement of thick ascending limb (TAL) NaCl transport in response to long-term increases in… (More)
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Highly Cited
1998
Highly Cited
1998
The epithelial sodium-hydrogen antiporter Na+/H+ exchanger 3 accumulates and is functional in recycling endosomes.
Na+/H+ exchangers (NHEs) mediate electroneutral exchange of Na+ for H+ and thereby play a central role in pH regulation and Na… (More)
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Highly Cited
1998
Highly Cited
1998
The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange.
Stimulation of beta2-adrenergic receptors on the cell surface by adrenaline or noradrenaline leads to alterations in the… (More)
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Highly Cited
1997
Highly Cited
1997
Monoclonal antibodies for high-resolution localization of NHE3 in adult and neonatal rat kidney.
Previous immunochemical studies have shown that NHE3 is an apical Na+/H+ exchanger in some renal epithelia. The purpose of the… (More)
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Highly Cited
1995
Highly Cited
1995
Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb.
Apical membrane Na/H exchange is a principal mechanism of renal proximal tubule Na absorption and H secretion, and thick… (More)
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Highly Cited
1995
Highly Cited
1995
Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion.
OBJECTIVE The aim was to characterise the new compound HOE642 as a selective and cardioprotective Na+/H+ exchange inhibitor in… (More)
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Highly Cited
1992
Highly Cited
1992
Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally…
Biochemical and pharmacological data support the existence of multiple forms of the Na/H exchanger (NHE). Two isoforms, termed… (More)
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