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Sodium/Nucleoside Cotransporter 1

Known as: CNT 1, Solute Carrier Family 28 Member 1, Sodium-Coupled Nucleoside Transporter 1 
Sodium/nucleoside cotransporter 1 (649 aa, ~72 kDa) is encoded by the human SLC28A1 gene. This protein is involved in sodium-mediated transport of… Expand
National Institutes of Health

Papers overview

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2015
2015
Nucleoside analogs are used as chemotherapeutic options for the treatment of platinum-resistant ovarian cancers. Human… Expand
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2013
2013
Nucleoside transporters (NTs) mediate the uptake of nucleosides and nucleobases across the plasma membrane, mostly for salvage… Expand
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Highly Cited
2010
Highly Cited
2010
18F-3′-Deoxy-3′-fluorothymidine (18F-FLT) is a PET tracer that accumulates in proliferating tissues. The current study was… Expand
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2010
2010
Mizoribine, an immunosuppressive anti-metabolite, is largely excreted into urine in its unchanged form, and its pharmacokinetics… Expand
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2010
2010
PURPOSE To assess the efficacy of 2-chloro-2'-deoxyadenosine (2-CdA) given subcutaneously (SC) in combination with rituximab in… Expand
Highly Cited
2004
Highly Cited
2004
Many antiviral drugs (e.g. fialuridine; FIAU) produce clinically significant mitochondrial toxicity that limits their dose or… Expand
Highly Cited
2004
Highly Cited
2004
Human concentrative nucleoside transporter 1 (hCNT1) mediates active transport of nucleosides and anticancer and antiviral… Expand
2004
2004
BACKGROUND/AIMS Concentrative nucleoside transporter 1 (CNT1), a high affinity transporter for pyrimidine nucleosides, is… Expand
Highly Cited
2003
Highly Cited
2003
We previously showed that the exocyst complex specifically affected the synthesis and delivery of secretory and basolateral… Expand
2001
2001
Many nucleosides undergo active reabsorption within the kidney, probably via nucleoside transporters. To date, two concentrative… Expand
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