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Smoothened Receptor

Known as: Receptor, Smoothened, Smoothened Receptor [Chemical/Ingredient], Receptors, Smoothened 
A frizzled-like, G-protein-coupled receptor that associates with PATCHED RECEPTORS to transduce signals from HEDGEHOG PROTEINS and initiate hedgehog… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
The Smoothened receptor (SMO) belongs to the Class Frizzled of the G protein-coupled receptor (GPCR) superfamily, constituting a… Expand
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Highly Cited
2014
Highly Cited
2014
The Smoothened receptor (SMO) mediates signal transduction in the hedgehog pathway, which is implicated in normal development and… Expand
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2014
2014
BACKGROUND The smoothened (SMO) receptor, one of the Class F G protein coupled receptors (GPCRs), is an essential component of… Expand
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Highly Cited
2014
Highly Cited
2014
Background: Epigenetic regulation plays an important role in cancer-associated signaling pathways. Results: The bromodomain… Expand
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Highly Cited
2013
Highly Cited
2013
The smoothened (SMO) receptor, a key signal transducer in the hedgehog signalling pathway, is responsible for the maintenance of… Expand
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Highly Cited
2010
Highly Cited
2010
The blockade of aberrant hedgehog (Hh) signaling has shown promise for therapeutic intervention in cancer. A cell-based… Expand
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Highly Cited
2009
Highly Cited
2009
Recent work has shown that primary cilia are essential for Hedgehog (Hh) signaling during mammalian development. It is also known… Expand
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Highly Cited
2009
Highly Cited
2009
The Smoothened receptor (Smo) mediates hedgehog (Hh) signaling critical for development, cell growth, and migration, as well as… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The Hedgehog (Hh) family of secreted proteins is involved in a number of developmental processes as well as in cancer… Expand
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Highly Cited
1996
Highly Cited
1996
MEMBERS of the Hedgehog family of secreted proteins control a number of important inductive interactions in the development of… Expand
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