Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity

Known as: UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase activity, UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase activity, UDP-N-acetyl-D-glucosamine:Skp1-protein-hydroxyproline N-acetyl-D-glucosaminyl-transferase activity 
Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline. [EC… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling.
We have previously demonstrated that in a rat model of trauma-hemorrhage (T-H), glucosamine administration during resuscitation… (More)
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Highly Cited
2009
Highly Cited
2009
In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation.
O-Linked N-acetylglucosamine (O-GlcNAc) is a cytosolic and nuclear carbohydrate post-translational modification most abundant in… (More)
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Highly Cited
2008
Highly Cited
2008
Cardioprotection by N-acetylglucosamine linkage to cellular proteins.
BACKGROUND The modification of proteins with O-linked beta-N-acetylglucosamine (O-GlcNAc) represents a key posttranslational… (More)
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Review
2007
Review
2007
Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system.
There is growing recognition that the O-linked attachment of N-acetyl-glucosamine (O-GlcNAc) on serine and threonine residues of… (More)
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Highly Cited
2007
Highly Cited
2007
Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart.
Increased levels of O-linked attachment of N-acetylglucosamine (O-GlcNAc) on nucleocytoplasmic proteins are implicated in the… (More)
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Highly Cited
2006
Highly Cited
2006
Increased hexosamine biosynthesis and protein O-GlcNAc levels associated with myocardial protection against calcium paradox and ischemia.
Increased hexosamine biosynthesis pathway (HBP) flux and elevated levels of protein O-linked-N-acetylglucosamine (O-GlcNAc… (More)
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Highly Cited
2005
Highly Cited
2005
Fragmentation of negative ions from carbohydrates: part 3. Fragmentation of hybrid and complex N-linked glycans.
Hybrid and complex N-linked glycans were ionized by electrospray in the presence of ammonium nitrate to give [M + NO3]- and [M… (More)
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Highly Cited
2005
Highly Cited
2005
O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes
It has been known that O-linked β-N-acetylglucosamine (O-GlcNAc) modification of proteins plays an important role in… (More)
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Highly Cited
1992
Highly Cited
1992
Structures of the asparagine-linked oligosaccharide chains of human von Willebrand factor. Occurrence of blood group A, B, and H(O) structures.
The asparagine-linked oligosaccharide chains of human von Willebrand factor (vWF) purified from pooled plasma were quantitatively… (More)
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Highly Cited
1990
Highly Cited
1990
Evidence for the nature of the link between the arabinogalactan and peptidoglycan of mycobacterial cell walls.
The long-posed question of the nature of the link between the mycolylarabinogalactan and the underlying peptidoglycan of the cell… (More)
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