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Kinetic, thermodynamic, and structural properties of the aminoglycoside N3-acetyltransferase-VIa (AAC-VIa) are determined. Among… (More)
Sisomicin is a new aminoglycoside similar to gentamicin in chemical structure and antibacterial spectrum. The in vitro activity… (More)
Sisomicin was isolated from fermentation broths of a new species of the genus Micromonospora, specifically M. inyoensis, and was… (More)
Das Aminoglykosid-Antibiotikum Sisomicin wurde in einer Reihe von Untersuchungsserien auf seine antibakterielle Aktivität geprüft… (More)
Sisomicin, the principal antibiotic produced in the fermentation of Micromonospora inyoensis, has the chemical structure 0-2,6… (More)
The binding of several aminoglycoside antibiotics to human serum proteins was studied under varying experimental conditions. The… (More)