Single-Stranded RNA

Known as: ssRNA 
An RNA that consists of a single strand of ribonucleotides. Because it lacks a complementary strand this form of RNA can adopt unique tertiary… (More)

Topic mentions per year

Topic mentions per year

1967-2018
05010019672018

Papers overview

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Highly Cited
2008
Highly Cited
2008
The human obesity susceptibility gene, FTO, encodes a protein that is homologous to the DNA repair AlkB protein. The AlkB family… (More)
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Highly Cited
2008
Highly Cited
2008
A DExD/H protein, RIG-I, is critical in innate antiviral responses by sensing viral RNA. Here we show that RIG-I recognizes two… (More)
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Highly Cited
2006
Highly Cited
2006
Double-stranded RNA (dsRNA) produced during viral replication is believed to be the critical trigger for activation of antiviral… (More)
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Highly Cited
2006
Highly Cited
2006
The Drosha-DGCR8 complex initiates microRNA maturation by precise cleavage of the stem loops that are embedded in primary… (More)
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Highly Cited
2005
Highly Cited
2005
Short interfering RNAs (siRNAs) that mediate specific gene silencing through RNA interference (RNAi) are widely used to study… (More)
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Highly Cited
2004
Highly Cited
2004
Double-stranded ribonucleic acid (dsRNA) serves as a danger signal associated with viral infection and leads to stimulation of… (More)
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Highly Cited
2004
Highly Cited
2004
Interferons (IFNs) are critical for protection from viral infection, but the pathways linking virus recognition to IFN induction… (More)
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Highly Cited
2002
Highly Cited
2002
A monoclonal antibody (mAb) against human Toll-like receptor (TLR) 3 was established and its effect on TLR3-mediated responses… (More)
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Highly Cited
2000
Highly Cited
2000
Members of the double-stranded RNA- (dsRNA) specific adenosine deaminase gene family convert adenosine residues into inosines in… (More)
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Highly Cited
1998
Highly Cited
1998
Protein interactions with double-stranded RNA (dsRNA) are critical for many cell processes; however, in contrast to protein-dsDNA… (More)
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