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Silmitasertib Sodium
Known as:
5-((3-chlorophenyl)amino)-benzo(c)-2,6-naphthyridine-8-carboxylic Acid Sodium Salt
, CK2 Inhibitor CX-4945
The sodium salt of silmitasertib, an orally bioavailable small-molecule inhibitor of CK2 with potential antineoplastic activity. Silmitasertib…
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National Institutes of Health
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3 relations
CX 4945
NCIt Antineoplastic Agent Terminology
Silmitasertib
Papers overview
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2012
2012
Human Cancer Biology Protein KinaseCK 2 ProtectsMultipleMyelomaCells fromER Stress – Induced Apoptosis and from the Cytotoxic Effect of HSP 90 Inhibition through Regulation of the Unfolded Protein…
S. Manni
,
Alessandra Brancalion
,
+16 authors
F. Piazza
2012
Corpus ID: 38648742
Purpose: Protein kinase CK2 promotes multiple myeloma cell growth by regulating critical signaling pathways. CK2 also modulates…
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2011
2011
Abstract 2560: The CK2 inhibitor CX-4945 enhances the antitumor activity of EGFR-targeted agents by attenuating signaling in the PI3K/AKT/mTOR pathway
J. Bliesath
,
D. Drygin
,
+7 authors
K. Anderes
2011
Corpus ID: 71824363
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL The epidermal growth factor receptor (EGFR) regulates…
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