Sialic Acid Binding Ig-like Lectin 1

Known as: Sialoadhesin, CD169 Antigens, Siglec-1 
A sialic acid binding lectin that was originally identified as an adhesion molecule for inflammatory MACROPHAGES and activated MONOCYTES. This… (More)
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
Diagnosis of the autoimmune disease type 1 diabetes (T1D) is preceded by the appearance of circulating autoantibodies to… (More)
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Highly Cited
2012
Highly Cited
2012
Dendritic cells (DCs) are essential antigen-presenting cells for the induction of immunity against pathogens. However, HIV-1… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Type I interferon (IFN) plays a pivotal role in the pathogenesis of systemic lupus erythematosus (SLE) and is therefore… (More)
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Highly Cited
2008
Highly Cited
2008
The porcine reproductive and respiratory syndrome virus (PRRSV) shows a restricted tropism for subsets of porcine macrophages in… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND HIV-1 infection dysregulates the immune system and alters gene expression in circulating monocytes. Differential gene… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Microarray analyses of peripheral blood leukocytes have shown that patients with systemic lupus erythematosus express… (More)
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Highly Cited
2001
Highly Cited
2001
Sialoadhesin is a macrophage-restricted cellular interaction molecule and a prototypic member of the Siglec family of sialic acid… (More)
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Highly Cited
2000
Highly Cited
2000
The common sialic acids of mammalian cells are N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc). Humans… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND Protein-carbohydrate interactions are believed to be important in many biological processes that involve cell-cell… (More)
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Highly Cited
1991
Highly Cited
1991
Macrophage subpopulations in the mouse express a lectin-like receptor, sialoadhesin (originally named sheep erythrocyte receptor… (More)
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