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Sialic Acid Binding Ig-like Lectin 1

Known as: Sialoadhesin, CD169 Antigens, Siglec-1 
A sialic acid binding lectin that was originally identified as an adhesion molecule for inflammatory MACROPHAGES and activated MONOCYTES. This… Expand
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
Diagnosis of the autoimmune disease type 1 diabetes (T1D) is preceded by the appearance of circulating autoantibodies to… Expand
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Highly Cited
2010
Highly Cited
2010
The porcine reproductive and respiratory syndrome virus (PRRSV) is a major threat to swine health worldwide and is considered the… Expand
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Type I interferon (IFN) plays a pivotal role in the pathogenesis of systemic lupus erythematosus (SLE) and is therefore… Expand
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Highly Cited
2008
Highly Cited
2008
The porcine reproductive and respiratory syndrome virus (PRRSV) shows a restricted tropism for subsets of porcine macrophages in… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Microarray analyses of peripheral blood leukocytes have shown that patients with systemic lupus erythematosus express… Expand
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Highly Cited
2001
Highly Cited
2001
Sialoadhesin is a macrophage-restricted cellular interaction molecule and a prototypic member of the Siglec family of sialic acid… Expand
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Highly Cited
2000
Highly Cited
2000
The common sialic acids of mammalian cells areN-acetylneuraminic acid (Neu5Ac) andN-glycolylneuraminic acid (Neu5Gc). Humans are… Expand
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Highly Cited
1995
Highly Cited
1995
CD33 is a member of the Ig superfamily that is restricted to cells of the myelomonocytic lineage but whose functions and binding… Expand
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Highly Cited
1994
Highly Cited
1994
BACKGROUND Protein-carbohydrate interactions are believed to be important in many biological processes that involve cell-cell… Expand
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Highly Cited
1994
Highly Cited
1994
Sialoadhesin is a macrophage‐restricted adhesion molecule of 185 kDa that mediates sialic acid‐dependent binding to cells. It is… Expand
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