Shc Signaling Adaptor Proteins

Known as: Shc Family Adapter Proteins, Shc Adaptor Proteins, Adaptor Proteins, Shc 
A family of signaling adaptor proteins that contain SRC HOMOLOGY DOMAINS. Many members of this family are involved in transmitting signals from CELL… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2017
012319962017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
OBJECTIVE To increase the power of nasal potential difference (NPD) as a biomarker of CFTR function, improvement of its… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2008
2008
Individual protein tyrosine kinases and phosphatases target multiple substrates; this may generate conflicting signals, possibly… (More)
Is this relevant?
2005
2005
N-Shc (neural Shc) (also ShcC), an adapter protein possessing two phosphotyrosine binding motifs [PTB (phosphotyrosine binding… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2002
2002
beta-Amyloid precursor protein (APP) is a widely expressed transmembrane protein of unknown function that is involved in the… (More)
Is this relevant?
2002
2002
Neurotrophins are key regulators of the fate and shape of neuronal cells and act as guidance cues for growth cones by remodeling… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2002
2002
Neurotrophins (NTs) have multiple roles in retinal development and survival, which are mediated through their specific receptors… (More)
Is this relevant?
1999
1999
Our recent studies revealed that the inositol phosphatase Src homology 2 (SH2) domain-containing inositol phosphatase (SHIP) is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1998
1998
The Shc adapter protein is ubiquitously expressed and has been implicated in phosphotyrosine signalings following a variety of… (More)
Is this relevant?
1996
1996
Shc has been implicated in a variety of growth factor- and cytokine receptor-signaling through its specific binding to… (More)
Is this relevant?
1996
1996
Shc has two distinct domains, amino-terminal and SH2 domain, which can interact with activated growth factor receptors. Shc… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?