Shc Signaling Adaptor Proteins
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β-Amyloid precursor protein (APP) is a widely expressed transmembrane protein of unknown function that is involved in the… Expand We determined the gene structure of the human TrkB gene. The gene is unusually large and spans at least 590 kbp. It contains 24… Expand ABSTRACT Neurotrophins are key regulators of the fate and shape of neuronal cells and act as guidance cues for growth cones by… Expand The Met receptor tyrosine kinase is the prototypic member of a small subfamily of growth factor receptors that when activated… Expand The receptor for insulin-like growth factor 1 (IGF-1) mediates multiple cellular responses, including stimulation of both… Expand We have used the yeast two-hybrid system to study the interaction between the IGF-I receptor and two putative substrates, IRS-1… Expand Germ line mutations of the ret proto-oncogene are associated with the development of three dominantly inherited neoplastic… Expand The most striking feature that the PDZ and PTB complexes have in common is also the augmentation of a β-sheet by addition of an… Expand Shc has been implicated in a variety of growth factor- and cytokine receptor-signaling through its specific binding to… Expand A new one-transistor, one-capacitor RAM cell structure called a Quadruply Self-Aligned Stacked High Capacitance (QSA SHC) RAM is… Expand