Severe congenital neutropenia

Known as: genetic infantile agranulocytosis, Congenital Neutropenia, agranulocytosis genetic infantile 
An inherited disorder in which there is a lower-than-normal number of neutrophils (a type of white blood cell that is important in fighting… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
0204019572017

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND The main features of severe congenital neutropenia are the onset of severe bacterial infections early in life, a… (More)
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Highly Cited
2007
Highly Cited
2007
Autosomal recessive severe congenital neutropenia (SCN) constitutes a primary immunodeficiency syndrome associated with increased… (More)
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Highly Cited
2006
Highly Cited
2006
In patients with severe congenital neutropenia (SCN), sepsis mortality is reduced by treatment with granulocyte colony… (More)
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Highly Cited
2006
Highly Cited
2006
Severe congenital neutropenia (SCN) is characterized by neutropenia, recurrent bacterial infections, and maturation arrest in the… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND AND OBJECTIVES The two main complications of severe chronic neutropenia are fatal sepsis and myelodysplasia/acute… (More)
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Highly Cited
2001
Highly Cited
2001
The Wiskott-Aldrich syndrome protein (WASP; encoded by the gene WAS) and its homologs are important regulators of the actin… (More)
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2001
2001
Severe congenital neutropenia is a heritable human disorder characterized by neutropenia and acute myelogenous leukemia. We… (More)
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Highly Cited
2000
Highly Cited
2000
Congenital neutropenia and cyclic neutropenia are disorders of neutrophil production predisposing patients to recurrent bacterial… (More)
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Highly Cited
1993
Highly Cited
1993
Patients with idiopathic, cyclic, and congenital neutropenia have recurrent severe bacterial infections. One hundred twenty-three… (More)
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1976
1976
The pathogenesis of the granulopoietic failure in three children with severe congenital neutropenia was studied. Mature… (More)
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