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Serine/Threonine Phosphorylation

Serine/Threonine Phosphorylation involves covalent linkage of a phosphate group (from a donor compound such as ATP) with a serine or threonine… Expand
National Institutes of Health

Papers overview

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Review
2012
Review
2012
The insulin receptor substrate proteins IRS1 and IRS2 are key targets of the insulin receptor tyrosine kinase and are required… Expand
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Highly Cited
2002
Highly Cited
2002
Wnt regulation of beta-catenin degradation is essential for development and carcinogenesis. beta-catenin degradation is initiated… Expand
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Highly Cited
2002
Highly Cited
2002
Diffuse large B-cell lymphoma (DLBCL), the most common lymphoid malignancy in adults, is curable in less than 50% of patients… Expand
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Highly Cited
2002
Highly Cited
2002
The growth factor‐activated AGC protein kinases RSK, S6K, PKB, MSK and SGK are activated by serine/threonine phosphorylation in… Expand
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Highly Cited
2001
Highly Cited
2001
Insulin receptor substrate (IRS)-1 protein expression is markedly reduced in many insulin-resistant states, although the… Expand
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Highly Cited
1996
Highly Cited
1996
The highly conserved and ubiquitously expressed 14-3-3 family of proteins bind to a variety of proteins involved in signal… Expand
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Highly Cited
1994
Highly Cited
1994
Treatment of cells with okadaic acid, a protein phosphatase inhibitor, leads to an insulin-resistant state without modification… Expand
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Highly Cited
1994
Highly Cited
1994
The enzyme glycogen synthase kinase-3 (GSK-3) has been implicated in the control of several metabolic enzymes and transcription… Expand
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Highly Cited
1992
Highly Cited
1992
A cDNA encoding the TGF-beta type II receptor protein has been isolated by an expression cloning strategy. The cloned cDNA, when… Expand
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Highly Cited
1991
Highly Cited
1991
We recently described the purification and cloning of extracellular signal-regulated kinase 1 (ERK1), which appears to play a… Expand
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