Serine/Threonine Phosphorylation

Serine/Threonine Phosphorylation involves covalent linkage of a phosphate group (from a donor compound such as ATP) with a serine or threonine… (More)
National Institutes of Health

Papers overview

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Review
2012
Review
2012
The insulin receptor substrate proteins IRS1 and IRS2 are key targets of the insulin receptor tyrosine kinase and are required… (More)
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2005
2005
Prolidase [E.C. 3.4.13.9], a member of the matrix metalloproteinase (MMP) family, is a manganese-dependent cytosolic exopeptidase… (More)
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Highly Cited
2002
Highly Cited
2002
Wnt regulation of beta-catenin degradation is essential for development and carcinogenesis. beta-catenin degradation is initiated… (More)
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Highly Cited
2002
Highly Cited
2002
Diffuse large B-cell lymphoma (DLBCL), the most common lymphoid malignancy in adults, is curable in less than 50% of patients… (More)
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Highly Cited
2001
Highly Cited
2001
Insulin receptor substrate (IRS)-1 protein expression is markedly reduced in many insulin-resistant states, although the… (More)
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Highly Cited
2001
Highly Cited
2001
Serine/threonine phosphorylation of IRS-1 might inhibit insulin signaling, but the relevant phosphorylation sites are difficult… (More)
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Highly Cited
2000
Highly Cited
2000
Insulin receptor substrate-1 (IRS-1) is a major substrate of the insulin receptor and acts as a docking protein for Src homology… (More)
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Highly Cited
1997
Highly Cited
1997
Tumor necrosis factor alpha (TNFalpha) or chronic hyperinsulinemia that induce insulin resistance trigger increased Ser/Thr… (More)
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Highly Cited
1996
Highly Cited
1996
Okadaic acid has been described previously as being a negative regulator of insulin signaling, as it inhibits insulin stimulation… (More)
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Highly Cited
1996
Highly Cited
1996
The highly conserved and ubiquitously expressed 14-3-3 family of proteins bind to a variety of proteins involved in signal… (More)
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