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Senile Plaques
Known as:
amyloid plaques
, Neuritic Plaque
, Braindruse
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Senile plaques are extracellular deposits of amyloid in the gray matter of the brain. [HPO:sdoelken]
National Institutes of Health
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Related topics
Related topics
10 relations
Alzheimer's Disease
Amyloid
Amyloid Proteins
Amyloid beta-Peptides
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Broader (3)
Nerve Degeneration
Neurons
Plaque, Amyloid
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
NIA-AA Research Framework: Toward a biological definition of Alzheimer’s disease
C. Jack
,
D. Bennett
,
+17 authors
R. Sperling
Alzheimer's & Dementia
2018
Corpus ID: 205672766
Review
2004
Review
2004
Neuropathological stageing of Alzheimer-related changes
H. Braak
,
E. Braak
Acta Neuropathologica
2004
Corpus ID: 668690
SummaryEighty-three brains obtained at autopsy from nondemented and demented individuals were examined for extracellular amyloid…
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Review
2002
Review
2002
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
J. Hardy
,
D. Selkoe
Science
2002
Corpus ID: 15150253
It has been more than 10 years since it was first proposed that the neurodegeneration in Alzheimer's disease (AD) may be caused…
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Highly Cited
1996
Highly Cited
1996
Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice
K. Hsiao
,
P. Chapman
,
+5 authors
G. Cole
Science
1996
Corpus ID: 32419070
Transgenic mice overexpressing the 695-amino acid isoform of human Alzheimer β-amyloid (Aβ) precursor protein containing a Lys670…
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Highly Cited
1992
Highly Cited
1992
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
P. Arriagada
,
J. Growdon
,
E. Hedley‐Whyte
,
B. Hyman
Neurology
1992
Corpus ID: 34398894
We studied the accumulation of neurofibrillary tangles (NFTs) and senile plaques (SPs) in 10 Alzheimer's disease patients who had…
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Highly Cited
1992
Highly Cited
1992
Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
D. Celermajer
,
K. Sørensen
,
+5 authors
J. Deanfield
The Lancet
1992
Corpus ID: 12042839
Review
1991
Review
1991
Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease
R. DeFronzo
,
E. Ferrannini
Diabetes Care
1991
Corpus ID: 41910286
Diabetes mellitus is commonly associated with systolic/diastolic hypertension, and a wealth of epidemiological data suggest that…
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Highly Cited
1978
Highly Cited
1978
Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.
E. Perry
,
B. Tomlinson
,
G. Blessed
,
K. Bergmann
,
P. Gibson
,
R. Perry
British medical journal
1978
Corpus ID: 7111142
Necropsy brain tissue from normal (control) patients and patients with depression and dementia was examined for activities of…
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Highly Cited
1973
Highly Cited
1973
A new technique for the assay of infectivity of human adenovirus 5 DNA.
F. Graham
,
A. van der Eb
Virology
1973
Corpus ID: 8204684
Review
1968
Review
1968
The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects
G. Blessed
,
B. Tomlinson
,
M. Roth
British Journal of Psychiatry
1968
Corpus ID: 42670035
The ageing of many populations in recent years has directed increasing attention to the social, medical and biological problems…
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