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Senile Plaques

Known as: amyloid plaques, Neuritic Plaque, Braindruse 
Senile plaques are extracellular deposits of amyloid in the gray matter of the brain. [HPO:sdoelken]
National Institutes of Health

Related topics

Related topics

10 relations
Alzheimer's DiseaseAmyloidAmyloid ProteinsAmyloid beta-Peptides
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Broader (3)

Nerve DegenerationNeuronsPlaque, Amyloid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
Neuropathological stageing of Alzheimer-related changes
SummaryEighty-three brains obtained at autopsy from nondemented and demented individuals were examined for extracellular amyloid… Expand
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Review
2002
Review
2002
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
It has been more than 10 years since it was first proposed that the neurodegeneration in Alzheimer's disease (AD) may be caused… Expand
Highly Cited
1998
Highly Cited
1998
Copper, iron and zinc in Alzheimer's disease senile plaques
Concentrations of copper (Cu), iron (Fe) and zinc (Zn) were measured in the rims and cores of senile plaques (SP) and in the… Expand
Highly Cited
1996
Highly Cited
1996
Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice
Transgenic mice overexpressing the 695-amino acid isoform of human Alzheimer β-amyloid (Aβ) precursor protein containing a Lys670… Expand
Highly Cited
1992
Highly Cited
1992
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
We studied the accumulation of neurofibrillary tangles (NFTs) and senile plaques (SPs) in 10 Alzheimer's disease patients who had… Expand
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Highly Cited
1992
Highly Cited
1992
Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
Endothelial dysfunction is an early event in experimental studies of atherogenesis, preceding formation of plaques. We have… Expand
Review
1991
Review
1991
Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease
Diabetes mellitus is commonly associated with systolic/diastolic hypertension, and a wealth of epidemiological data suggest that… Expand
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Highly Cited
1978
Highly Cited
1978
Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.
Necropsy brain tissue from normal (control) patients and patients with depression and dementia was examined for activities of… Expand
Highly Cited
1973
Highly Cited
1973
A new technique for the assay of infectivity of human adenovirus 5 DNA.
Abstract A new technique for assaying infectivity of adenovirus 5 DNA has been developed. Viral DNA was diluted in isotonic… Expand
Highly Cited
1968
Highly Cited
1968
The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects.
1. The association between plaque counts in sections of cerebral cortex and measures of intellectual and personality functioning… Expand
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