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SummaryEighty-three brains obtained at autopsy from nondemented and demented individuals were examined for extracellular amyloid… Expand It has been more than 10 years since it was first proposed that the neurodegeneration in Alzheimer's disease (AD) may be caused… Expand Concentrations of copper (Cu), iron (Fe) and zinc (Zn) were measured in the rims and cores of senile plaques (SP) and in the… Expand Transgenic mice overexpressing the 695-amino acid isoform of human Alzheimer β-amyloid (Aβ) precursor protein containing a Lys670… Expand We studied the accumulation of neurofibrillary tangles (NFTs) and senile plaques (SPs) in 10 Alzheimer's disease patients who had… Expand Endothelial dysfunction is an early event in experimental studies of atherogenesis, preceding formation of plaques. We have… Expand Diabetes mellitus is commonly associated with systolic/diastolic hypertension, and a wealth of epidemiological data suggest that… Expand Necropsy brain tissue from normal (control) patients and patients with depression and dementia was examined for activities of… Expand Abstract A new technique for assaying infectivity of adenovirus 5 DNA has been developed. Viral DNA was diluted in isotonic… Expand 1. The association between plaque counts in sections of cerebral cortex and measures of intellectual and personality functioning… Expand