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Sch 221510

Known as: Sch-221510, Sch221510 
National Institutes of Health

Papers overview

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2018
2018
A Novel and Selective Nociceptin Receptor (NOP) Agonist (1‐(1‐((cis)‐4‐isopropylcyclohexyl)piperidin‐4‐yl)‐1H‐indol‐2‐yl)methanol (AT‐312) Decreases Acquisition of Ethanol‐Induced Conditioned Place…
BACKGROUND Nociceptin/orphanin FQ, the endogenous peptide agonist for the opioid receptor-like receptor (also known as NOP or the… 
2018
2018
ORL1 Activation Mediates a Novel ORL1 Receptor Agonist SCH221510 Analgesia in Neuropathic Pain in Rats
Opioid receptor like 1 (ORL1) receptor activation displayed an anti-nociceptive effect at spinal level for acute and neuropathic… 
2013
2013
Examining the reinforcing properties of NOP receptor agonist SCH221510 and its role in attenuating mu‐receptor mediated reinforcement in a rat self‐administration assay
Nociceptin/orphanin FQ receptor (NOP) plays a critical role in regulation of reward and motivation neuropathways. In rodents, NOP… 
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