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Sarcoplasmic Reticulum Calcium-Transporting ATPase 2a

Known as: SERCA2a Calcium ATPase, Sarcoplasmic Endoplasmic Reticulum Calcium ATPase 2a, Sarcoplasmic-Endoplasmic Reticulum Calcium ATPase 2a 
 
National Institutes of Health

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Sarcoplasmic Reticulum Calcium-Transporting ATPases

Papers overview

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2013
2013
Cardiac surgical delivery of the sarcoplasmic reticulum calcium ATPase rescues myocytes in ischemic heart failure.
BACKGROUND The sarcoplasmic reticulum calcium ATPase (SERCA2a) is an important molecular regulator of contractile dysfunction in… Expand
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2011
2011
Calcium handling in the failing heart and SUMO--weighing the evidence.
Heart failure has been attributed to a deficiency in a calcium ATPase. A recent study shows that tweaking this enzyme may boost… Expand
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2007
2007
Abstract 1083: Targeted SERCA2a Gene Overexpression Identifies Mechanism and Potential Therapy for Arrhythmogenic Cardiac Alternans
Background: Beat to beat alternation of the cardiac action potential (V m -Alt) attributable to alternation in cellular calcium… Expand
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2006
2006
[Treatment of chronic heart failure by overexpressing sarcoplasmic reticulum calcium ATPase through gene therapy: an experiment with rats].
OBJECTIVE To evaluate the value of sarcoplasmic reticulum Ca(2+)-ATPase (SERCA2a) in the gene therapy of congestive heart failure… Expand
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2006
2006
Cross-linking of C-terminal residues of phospholamban to the Ca2+ pump of cardiac sarcoplasmic reticulum to probe spatial and functional interactions within the transmembrane domain.
Interactions between the transmembrane domains of phospholamban (PLB) and the cardiac Ca2+ pump (SERCA2a) have been investigated… Expand
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2005
2005
Role of leucine 31 of phospholamban in structural and functional interactions with the Ca2+ pump of cardiac sarcoplasmic reticulum.
The ability of two loss-of-function mutants, L31A and L31C, of phospholamban (PLB) to bind to and inhibit the Ca(2+) pump of… Expand
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2005
2005
Role of Leucine 31 of Phospholamban in Structural and Functional Interactions with the Ca 2 Pump of Cardiac
The ability of two loss-of-function mutants, L31A and L31C, of phospholamban (PLB) to bind to and inhibit the Ca pump of cardiac… Expand
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