Saposin D

Known as: SAP D Protein, SAP-D Protein 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2012
0119882012

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2012
2012
Saposin D-deficient (Sap-D(-/-)) mice develop polydipsia/polyuria and die prematurely due to renal failure with robust… (More)
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2008
2008
Saposin D is a sphingolipid activator protein required for the lysosomal breakdown of ceramide to a fatty acid and sphingosine by… (More)
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Review
2007
Review
2007
We have generated specific saposin A and D deficient mouse mutants by the gene targeting technology. Saposin A deficient mice… (More)
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2003
2003
Saposins (A, B, C, and D) are small sphingolipid activator proteins that are derived by proteolytic processing of a common… (More)
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2001
2001
Saposin (Sap) D is a late endosomal/lysosomal small protein, generated together with three other similar proteins, Sap A, B, and… (More)
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1994
1994
Ceramide is ubiquitously present in plasma membranes and plays a pivotal role in metabolism of sphingolipids. In addition… (More)
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1993
1993
The effect of saposins (A, B, C and D) on acid sphingomyelinase activity was determined using a crude human kidney… (More)
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1990
1990
Saposins (A, B, C, and D) are small glycoproteins required for the hydrolysis of sphingolipids by specific lysosomal hydrolases… (More)
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1988
1988
Saposin D, a newly discovered heat-stable, 10 kDa glycoprotein, was isolated from Gaucher spleen and purified to homogeneity… (More)
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