SYVN1 gene

Known as: DER3, KIAA1810, HMG-coA reductase degradation 1 homolog (S. cerevisiae) 
 
National Institutes of Health

Papers overview

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2011
2011
Protein ubiquitination is a key regulatory process essential to life at a cellular level; significant efforts have been made to… (More)
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Highly Cited
2010
Highly Cited
2010
Sophisticated quality control mechanisms prolong retention of protein-folding intermediates in the endoplasmic reticulum (ER… (More)
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2010
Highly Cited
2010
Wolfram syndrome is an autosomal-recessive disorder characterized by insulin-dependent diabetes mellitus, caused by nonautoimmune… (More)
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2008
Highly Cited
2008
Misfolded or improperly assembled proteins in the endoplasmic reticulum (ER) are exported into the cytosol and degraded via the… (More)
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2007
2007
E3 ubiquitin ligases catalyze the conjugation of ubiquitin onto proteins, which acts as a signal for targeting proteins for… (More)
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2006
Highly Cited
2006
The ubiquitin system targets many cellular proteins. Doa10 (also known as Ssm4), a yeast transmembrane ubiquitin ligase (E3… (More)
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2006
2006
It has been proposed that in autosomal recessive juvenile parkinsonism (AR-JP), a ubiquitin ligase (E3) Parkin, which is involved… (More)
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2004
2004
Endoplasmic reticulum (ER) stress, which is caused by the accumulation of misfolded proteins in the ER, elicits an adaptive… (More)
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2003
2003
Abnormally folded proteins are susceptible to aggregation and accumulation in cells, ultimately leading to cell death. To protect… (More)
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1996
Highly Cited
1996
3-hydroxy-3-methylglutaryl-CoA reductase (HMG-R), a key enzyme of sterol synthesis, is an integral membrane protein of the… (More)
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