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SYNJ1 protein, human

Known as: Synaptojanin 1, synaptojanin 1 protein, human, EC 3.1.3.36 
Synaptojanin-1 (1573 aa, ~173 kDa) is encoded by the human SYNJ1 gene. This protein plays a role in vesicle endocytosis.
National Institutes of Health

Related topics

Related topics

13 relations
Cytoplasmic matrixDephosphorylationEndocytosisEnzyme Gene

Broader (2)

Phosphatidylinositol-bisphosphatasesynaptojanin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Combining data integration and molecular dynamics for target identification in α-Synuclein-aggregating neurodegenerative diseases: Structural insights on Synaptojanin-1 (Synj1)
2020
2020
The lipid phosphatase Synaptojanin 1 undergoes a significant alteration in expression and solubility and is associated with brain lesions in Alzheimer’s disease
Synaptojanin 1 (SYNJ1) is a brain-enriched lipid phosphatase critically involved in autophagosomal/endosomal trafficking… 
2014
2014
Phosphatidylinositol 4,5-biphosphate (PIP2) modulates syntaxin-1A binding to sulfonylurea receptor 2A to regulate cardiac ATP-sensitive potassium (KATP) channels.
2008
2008
Janus-faced trafficking at glutamatergic synapses
Rapid communication in the nervous system requires the release and detection of neurotransmitters at synapses. These two events… 
Highly Cited
2004
Highly Cited
2004
A Novel AP-2 Adaptor Interaction Motif Initially Identified in the Long-splice Isoform of Synaptojanin 1, SJ170*
Phosphoinositides play a fundamental role in clathrin-coat assembly at the cell surface. Several endocytic components and… 
2004
2004
Protein kinases talk to lipid phosphatases at the synapse.
The ability to police membrane traffic in space and time reaches an especially high level of sophistication at presynaptic nerve… 
1998
1998
Localization of mRNAs for three splicing variants of synaptojanin-1 (SJ-1) in the central nervous system of pre- and postnatal rats
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