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STK11 protein, human
Known as:
Polarization-Related Protein LKB1
, liver kinase B1, human
, LKB1 protein, human
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Serine/threonine-protein kinase STK11 (433 aa, ~49 kDa) is encoded by the human STK11 gene. This protein plays a role in signal transduction and…
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National Institutes of Health
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Related topics
Related topics
16 relations
Adipocytokine Signaling Pathway
Apoptosis
Enzyme Gene
Peutz-Jeghers Syndrome
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Broader (1)
Protein-Serine-Threonine Kinases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Cyclin D 1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB 1 Signaling Axis
Mathew C. Casimiro
,
G. Sante
,
+15 authors
R. Pestell
2018
Corpus ID: 141067312
Autophagy activated after DNA damage or other stresses mitigates cellular damage by removing damaged proteins, lipids and…
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2017
2017
Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma.
Muge Celiktas
,
I. Tanaka
,
+13 authors
A. Taguchi
Journal of the National Cancer Institute
2017
Corpus ID: 47240034
Background Liver kinase B1 ( LKB1 ) is a tumor suppressor in lung adenocarcinoma (LADC). We investigated the proteomic profiles…
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2017
2017
Immunolocalisation of aromatase regulators liver kinase B1, phosphorylated AMP-activated protein kinase and cAMP response element-binding protein-regulated transcription co-activators in the human…
Seungmin Ham
,
K. Brown
,
E. Simpson
,
S. Meachem
Reproduction, Fertility and Development
2017
Corpus ID: 8930284
Although oestrogens are essential for spermatogenesis and their biosynthesis is dependent on aromatase expression, the molecular…
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2015
2015
Correction: Corrigendum: The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism
S. Pooya
,
Xiaona Liu
,
+9 authors
B. Dasgupta
Nature Communications
2015
Corpus ID: 29455326
Nature Communications 5: Article number: 4993 (2014); Published: 26 September 2014; Updated: 9 January 2015. The original version…
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2014
2014
Integrated Analysis of Transcriptomes of Cancer Cell Lines and Patient Samples Reveals STK11/LKB1–Driven Regulation of cAMP Phosphodiesterase-4D
Ningning He
,
Nayoung Kim
,
+10 authors
Sukjoon Yoon
Molecular Cancer Therapeutics
2014
Corpus ID: 36743287
The recent proliferation of data on large collections of well-characterized cancer cell lines linked to therapeutic drug…
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2013
2013
Metformin enhances cisplatin cytotoxicity by suppressing Stat 3 activity independently of the LKB 1 – AMPK pathway
Chien-Chung Lin
,
H. Yeh
,
+6 authors
W. Su
2013
Corpus ID: 207765343
2009
2009
Inactivation of HDAC 5 by SIK 1 in AICAR-treated C 2 C 12 Myoblasts
Takemori
,
K. Hashimoto
,
Nakae
,
N. Olson
,
Okamoto
2009
Corpus ID: 5547433
Salt inducible kinase (SIK) 1, a member of the AMP-activated kinase (AMPK) family, is activated by the AMPK-activator LKB1 which…
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2007
2007
LKB1, an upstream AMPK kinase, regulates glucose and lipid metabolism in cultured liver and muscle cells
今井 健太
2007
Corpus ID: 101845441
2006
2006
activated Protein Kinase Phosphorylation Inhibits Basal and Insulin-stimulated Glucose Uptake , Lipid Synthesis , and Fatty Acid Oxidation in Isolated Rat Adipocytes
M. P. Gaidhu
,
S. Fediuc
,
R. Ceddia
2006
Corpus ID: 29053721
The objective of this study was to investigate the effects of 5-aminoimidazole-4-carboxamide-1-D-ribofuranoside (AICAR)induced…
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2002
2002
Advances in Brief Hepatocellular Carcinoma Caused by Loss of Heterozygosity in Lkb 1 Gene Knockout Mice 1
M. Nakau
,
H. Miyoshi
,
M. Seldin
,
M. Imamura
,
M. Oshima
,
M. Taketo
2002
Corpus ID: 22796739
Germline mutations of the LKB1 gene are associated with PeutzJeghers syndrome, which is characterized by mucocutaneous…
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