STAT3 gene

Known as: STAT3, ACUTE-PHASE RESPONSE FACTOR, Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) Gene 
This gene plays a role in signal transduction and activation of transcription. It is involved in regulation of both apoptosis and cell growth.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Long noncoding RNAs (lncRNAs) play important roles in diverse biological processes; however, few have been identified that… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND T-cell large granular lymphocytic leukemia is a rare lymphoproliferative disorder characterized by the expansion of… (More)
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Highly Cited
2010
Highly Cited
2010
MicroRNA-155 (miR-155) is overexpressed in many human cancers; however, the mechanisms by which miR-155 functions as a putative… (More)
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Highly Cited
2009
Highly Cited
2009
Leukemia inhibitory factor (LIF) activates the transcription factor signal transducer and activator of transcription 3 (STAT3… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Hyper-IgE syndrome (HIES) is a rare, autosomal-dominant immunodeficiency characterized by eczema, Staphylococcus… (More)
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Highly Cited
2008
Highly Cited
2008
After activation, CD4(+) helper T (Th) cells differentiate into distinct effector subsets. Although chemokine (C-X-C motif… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The hyper-IgE syndrome (or Job's syndrome) is a rare disorder of immunity and connective tissue characterized by… (More)
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Highly Cited
2006
Highly Cited
2006
In the injured central nervous system (CNS), reactive astrocytes form a glial scar and are considered to be detrimental for… (More)
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Review
2005
Review
2005
The defense of the host from foreign pathogens is the commonly accepted function of the vertebrate immune system. A complex… (More)
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Highly Cited
2005
Highly Cited
2005
The constitutive activation of signal transducer and activator of transcription 3 (Stat3) is frequently detected in breast cancer… (More)
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