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STAT Inhibitor OPB-111077

Known as: OPB-111077 
An orally bioavailable inhibitor of one or more signal transducer and activator of transcription (STAT) protein(s), with potential antineoplastic… Expand
National Institutes of Health

Papers overview

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2019
2019
Purpose The signal transducer and activator of transcription 3 (STAT3) signaling pathway might be a promising therapeutic target… Expand
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2019
2019
Background The landscape of acute myeloid leukemia (AML) treatment has changed with the FDA approval of the oral Bcl-2 inhibitor… Expand
2018
2018
Abstract Lessons Learned. OPB‐111077 is a novel inhibitor of STAT3 and mitochondrial oxidative phosphorylation that exhibited… Expand
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2018
2018
4078Background: The signal transducer and activator of transcription 3 (STAT3) signaling pathway might be a promising therapeutic… Expand