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SS18 gene

Known as: SS18, SSXT, SYT 
This gene is involved in transcriptional activation.
National Institutes of Health

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Biphasic Synovial SarcomaCardiac Synovial SarcomaEpithelial Synovial SarcomaEsophageal Synovial Sarcoma

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SS18 wt Allele

Papers overview

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2012
2012
Vaccination using peptides spanning the SYT–SSX tumor-specific translocation
Evaluation of: Kawaguchi S, Tsukahara T, Ida K et al. SYT–SSX breakpoint peptide vaccines in patients with synovial sarcoma: a… 
2006
2006
Targeted disruption of the synovial sarcoma-associated SS18 gene causes early embryonic lethality and affects PPARBP expression.
The synovial sarcoma-associated protein SS18 (also known as SYT or SSXT) is thought to act as a transcriptional co-activator… 
2005
2005
Detection of SYT-SSX Rearrangements in Synovial Sarcomas by Real-Time One-Step RT-PCR
Synovial sarcomas are aggressive tumors of adolescent and young adults that account for up to 10% of soft tissue sarcomas… 
2005
2005
Reverse transcription-polymerase chain reaction in situ hybridization for SYT-SSX fusion gene transcripts in synovial sarcomas.
More than 90% of synovial sarcomas (SSs) possess a non-random chromosomal translocation t(X;18)(p11;q11) and express SYT-SSX… 
2003
2003
Characteristic sequence motifs located at the genomic breakpoints of the translocation t(X;18) in synovial sarcomas
The SYT–SSXI and SYT–SSX2 fusion genes, derived by reciprocal translocations t(X;18), are acquired genetic events strongly… 
2003
2003
Real-time Polymerase Chain Reaction as an Aid for the Detection of SYT-SSX1 and SYT-SSX2 Transcripts in Fresh and Archival Pediatric Synovial Sarcoma Specimens: Report of 25 Cases from St. Jude…
Synovial sarcoma is the most common nonrhabdomyosarcomatous soft tissue sarcoma in children and adolescents and is characterized… 
1999
1999
Histological and molecular evidence of synovial sarcoma of bone. A case report.
Synovial sarcoma is a clinically and morphologically well defined soft-tissue tumor that occurs predominantly in the extremities… 
1999
1999
A new human synovial sarcoma cell line, HS‐SY‐3, with a truncated form of hybrid SYT/SSX1 gene
Recent cytogenetical and molecular studies have indicated that synovial sarcoma harbors a t(X;18)(p11.2;q11.2) translocation… 
1998
1998
Characterization of a Variant SYT‐SSX1 Synovial Sarcoma Fusion Transcript
Synovial sarcoma is characterized cytogenetically by an X;18 translocation [t (X:18) (p11;q11)] that results in the fusion of the… 
1997
1997
Establishment and characterization of a new synovial sarcoma cell line, SN‐SY‐1: Special reference to bcl‐2 protein and SYT‐SSX1 hybrid transcripts
We established and characterized a new human synovial sarcoma cell line, SN‐SY‐1, derived from a monophasic fibrous synovial… 
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