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SS18-SSX1 fusion protein

Known as: SYT-SSX1 Fusion Protein, Protein SSXT/Protein SSX1 Fusion Protein, SS18/SSX1 Fusion Protein 
A fusion protein (488 aa, ~54 kDa) encoded by the SS18/SSX1 fusion gene. This protein is comprised of all but the last 8 amino acids of the C… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Fusion GeneSS18/SSX1 Fusion Gene

Broader (1)

Oncogene Proteins, Fusion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Prognostic implication of SYT–SSX fusion type and clinicopathological parameters for tumor‐related death, recurrence, and metastasis in synovial sarcoma
The present study aimed to describe the distribution and features of the SYT–SSX fusion gene in Chinese patients with synovial… Expand
Highly Cited
2006
Highly Cited
2006
SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by snail and slug: a potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma.
Synovial sarcoma is a primitive mesenchymal neoplasm characterized in almost all cases by a t(X;18) fusing the SYT… Expand
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Highly Cited
2002
Highly Cited
2002
Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients.
Synovial sarcomas are aggressive spindle cell sarcomas containing in some cases areas of epithelial differentiation. They… Expand
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2002
2002
Lack of SYT-SSX Fusion Transcripts in Malignant Peripheral Nerve Sheath Tumors on RT-PCR Analysis of 34 Archival Cases
The translocation t(X;18) is currently regarded as a specific molecular marker of synovial sarcoma (SS). Recently, however, it… Expand
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Highly Cited
2001
Highly Cited
2001
Monophasic and biphasic synovial sarcomas abundantly express cancer/testis antigen ny‐eso‐1 but not mage‐a1 or ct7
Synovial sarcomas are high‐grade malignant mesenchymal tumors with biphasic (BSS) and monophasic (MSS) variants that carry a… Expand
2000
2000
Synovial sarcoma. A Scandinavian Sarcoma Group project
  • B. Skytting
  • Acta orthopaedica Scandinavica. Supplementum
  • 2000
    • Corpus ID: 38355400
UNLABELLED Synovial sarcoma accounts for 5-10% of all soft tissue sarcomas. More than 90% are found in the extremities or trunk… Expand
Highly Cited
1999
Highly Cited
1999
Expression of insulin-like growth factor-1 receptor in synovial sarcoma: association with an aggressive phenotype.
It is well known that insulin-like growth factor-1 receptor (IGF-1R) plays a crucial role in proliferation and survival of… Expand
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Highly Cited
1999
Highly Cited
1999
The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome.
Cytogenetically, synovial sarcoma (SS) is characterized by the translocation t(X;18)(p11.2;q11.2), resulting in a fusion between… Expand
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Highly Cited
1999
Highly Cited
1999
Dual colour fluorescence in situ hybridization to paraffin‐embedded samples to deduce the presence of the der(X)t(X;18)(p11.2;q11.2) and involvement of either the SSX1 or SSX2 gene: a diagnostic and…
Identification of the t(X;18)(p11.2;q11.2) and the fusion gene products, SYT–SSX1 and SYT–SSX2, associated with a high proportion… Expand
Highly Cited
1998
Highly Cited
1998
SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma.
BACKGROUND Synovial sarcomas account for up to 10 percent of soft-tissue sarcomas and include two major histologic subtypes… Expand
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