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SS18-SSX1 fusion protein

Known as: SYT-SSX1 Fusion Protein, Protein SSXT/Protein SSX1 Fusion Protein, SS18/SSX1 Fusion Protein 
A fusion protein (488 aa, ~54 kDa) encoded by the SS18/SSX1 fusion gene. This protein is comprised of all but the last 8 amino acids of the C… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Fusion GeneSS18/SSX1 Fusion Gene

Broader (1)

Oncogene Proteins, Fusion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Prognostic implication of SYT-SSX fusion type and clinicopathological parameters for tumor-related death, recurrence, and metastasis in synovial sarcoma.
The present study aimed to describe the distribution and features of the SYT-SSX fusion gene in Chinese patients with synovial… Expand
Is this relevant?
Highly Cited
2006
Highly Cited
2006
SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by snail and slug: a potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma.
Synovial sarcoma is a primitive mesenchymal neoplasm characterized in almost all cases by a t(X;18) fusing the SYT… Expand
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Highly Cited
2002
Highly Cited
2002
Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients.
Synovial sarcomas are aggressive spindle cell sarcomas containing in some cases areas of epithelial differentiation. They… Expand
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2002
2002
Lack of SYT-SSX Fusion Transcripts in Malignant Peripheral Nerve Sheath Tumors on RT-PCR Analysis of 34 Archival Cases
The translocation t(X;18) is currently regarded as a specific molecular marker of synovial sarcoma (SS). Recently, however, it… Expand
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Is this relevant?
Highly Cited
2001
Highly Cited
2001
Monophasic and biphasic synovial sarcomas abundantly express cancer/testis antigen NY-ESO-1 but not MAGE-A1 or CT7.
Synovial sarcomas are high-grade malignant mesenchymal tumors with biphasic (BSS) and monophasic (MSS) variants that carry a… Expand
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2001
2001
c-KIT and c-KIT ligand (SCF) in synovial sarcoma (SS): an mRNA expression analysis in 23 cases
In a previous immunophenotypic molecular-based analysis it was shown that bcl2 over-expression characterizes the SS gene profile… Expand
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Highly Cited
1999
Highly Cited
1999
Expression of insulin-like growth factor-1 receptor in synovial sarcoma: association with an aggressive phenotype.
It is well known that insulin-like growth factor-1 receptor (IGF-1R) plays a crucial role in proliferation and survival of… Expand
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Highly Cited
1999
Highly Cited
1999
The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome.
Cytogenetically, synovial sarcoma (SS) is characterized by the translocation t(X;18)(p11.2;q11.2), resulting in a fusion between… Expand
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1999
1999
Dual colour fluorescence in situ hybridization to paraffin-embedded samples to deduce the presence of the der(X)t(X;18)(p11.2;q11.2) and involvement of either the SSX1 or SSX2 gene: a diagnostic and…
Identification of the t(X;18)(p11.2;q11.2) and the fusion gene products, SYT-SSX1 and SYT-SSX2, associated with a high proportion… Expand
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Highly Cited
1998
Highly Cited
1998
SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma.
BACKGROUND Synovial sarcomas account for up to 10 percent of soft-tissue sarcomas and include two major histologic subtypes… Expand
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