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SS1(dsFv)PE38

Known as: SS1P, Immunotoxin, SS1(dsFv)-PE38, SS1(dsFv) PE38 
A recombinant immunotoxin consisting of the single chain anti-mesothelin monoclonal antibody SS1(dsFv) linked to Pseudomonas exotoxin PE-38. The… 
National Institutes of Health

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3 relations

Broader (2)

ImmunotoxinsMonoclonal Antibodies
NCIt Antineoplastic Agent Terminology

Papers overview

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2019
2019
Abstract A142: Anti-mesothelin immunotoxins induce markers of immunogenic cell death and when injected locally into AE17M mesothelioma tumors enhance the effect of CTLA-4 blockade
Background: SS1P and LMB-100 are anti-mesothelin immunotoxins composed of a targeting antibody fragment genetically fused to a… 
2018
2018
Target : Src Pathway : Protein Tyrosine Kinase / RTK Solubility : DMSO : 18 . 5 mg / mL Caution
  • 2018
  • Corpus ID: 53706145
BIOLOGICAL ACTIVITY: SU 6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170… 
2017
2017
La réponse antitumorale des macrophages dirigée contre les cellules de mésothéliome pleural malin
Laboratoire de Biologie Cellulaire et Moleculaire de Gembloux Agro-Bio Tech (Universite de Liege) 
2014
2014
Large Molecule Therapeutics In Vitro and In Vivo Activity of the Low-Immunogenic Antimesothelin Immunotoxin RG 7787 in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, and new therapies are needed. RG7787 is a novel low-immunogenic… 
2014
2014
NEXT-GENERATION RECOMBINANT IMMUNOTOXINS FOR GLIOBLASTOMAS AND MELANOMAS TREATMENT
BACKGROUND: Glioblastoma (GBM) remains uniformly lethal despite the progress of conventional therapies, which lack specificity… 
2013
2013
Anti-Mesothelin Immunotoxin and Immune Suppression Major Cancer Regressions in Mesothelioma After Treatment with an
immunotoxin treatment. treating an aggressive and deadly tumor, and demonstrate a clever way to overcome immune rejection of… 
2012
2012
Combining the Recombinant Immunotoxin SS1P With the BH3-MIMETIC ABT-737 Induces Cell Death in Pancreatic Cancer Cells
2006
2006
Synergistic AntitumorActivity ofTaxol and Immunotoxin SS1P inTumor-BearingMice
Purpose:To investigate the combined antitumor activity inmice of immunotoxin SS1Pand Taxol. Methods: Immunodeficient mice were… 
2003
2003
PE38 幼児の他者の意図推測における情報利用に関する研究(発達,ポスター発表E)
2000
2000
PE38 小学校高学年児童の「学校における居場所」の研究 II : 自分の教室の居心地と教室空間に対するイメージ