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SPHK2 gene
Known as:
SPHINGOSINE KINASE 2
, SPHK2
, Sphingosine Kinase 2 Gene
This gene is involved in the biosynthesis of sphingosine 1- phosphate.
National Institutes of Health
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Related topics
Related topics
7 relations
Calcium Signaling
Negative Regulation of Apoptosis
Phospholipid Metabolism
Phosphorylation
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Title Sphingosine-1-phosphate signaling and biological activities in thecardiovascular system
Y. Takuwa
,
Y. Okamoto
,
K. Yoshioka
2017
Corpus ID: 20478746
The plasma lysophospholipid mediator sphingosine-1-phosphate (S1P) is produced exclusively by sphingosine kinase (SPHK) 1 and…
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2017
2017
Nuclear SphK2 and S1P Signaling Epigenetically Regulates Pseudomonas aeruginosa Induced Lung Inflammation
D. Ebenezer
2017
Corpus ID: 104425971
2016
2016
Abstract P1-03-03: Obesity increases the lipid mediator, sphingosine-1-phosphate in the tumor and tumor microenvironment, and promotes tumor progression
Junko Tsuchida
,
M. Nagahashi
,
+4 authors
T. Wakai
2016
Corpus ID: 77046350
INTRODUCTION: While obesity is an established independent prognostic factor for breast cancer patients, the underlying mechanisms…
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2016
2016
Structure Activity Relationship Studies on Isoform Selective Sphingosine Kinase Inhibitors
Molly D Congdon
2016
Corpus ID: 89655535
A variety of diseases including Alzheimer’s disease, asthma, cancer, fibrosis, multiple sclerosis, and sickle cell disease have…
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2016
2016
Genome-Wide DNA Methylation Assessment of ‘BRCA1-like’ Early-Onset Breast Cancer: data from the Australian Breast Cancer Family Registry
E. Wong
2016
Corpus ID: 263473472
2015
2015
AB0070 Deciphering the Functions of Sphingosine Kinases and Sphingosine-1-Phosphate Receptors in the Pathogenesis of Autoimmune Diseases: A Systems Immunological Approach
Peter Natesan Pushparaj
,
L. Damiati
,
S. Bahlas
2015
Corpus ID: 76833214
Background Sphingosine kinases (SPHKs) phosphorylate sphingosine (Sph) to sphingosine-1-phosphate (S1P). S1P is a pleiotropic…
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2014
2014
Due to Traumatic Brain Injury Sphingosine in Mitochondrial Dysfunction Essential Roles of Neutral Ceramidase and Lipids
I. Gudz
,
R. Proia
,
+4 authors
Christopher L. Riley
2014
Corpus ID: 79325984
2013
2013
A Selective Sphingosine Kinase 1 Inhibitor Integrates Multiple Molecular Therapeutic Targets in Human Leukemia
2013
Corpus ID: 263551436
Review
2011
Review
2011
Immune Regulation by Sphingosine 1-Phosphate and Its Receptors
C. Bode
,
M. Gräler
Archivum Immunologiae et Therapiae Experimentalis
2011
Corpus ID: 253601177
It is well established that the lysophospholipid and signalling molecule sphingosine 1-phosphate (S1P) has many important…
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2006
2006
Award Number: W81XWH-04-1-0393 TITLE: The Role of Sphingosine Kinase 2 in Apoptosis of Human Breast Cancer Cells
S. Spiegel
2006
Corpus ID: 51789265
s and Presentations Sankala H, Hait NC, Paugh SW, Milstien S, Spiegel S. p53 independent regulation of p21 expression by…
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