FAQ

SOX10 Transcription Factor

Known as: SOX 10 Transcription Factor, Transcription Factor, SOX10, SOX-10 Transcription Factor 
Transcription factor SOX-10 (466 aa, ~50 kDa) is encoded by the human SOX10 gene. This protein is involved in the regulation of gene expression.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
010203019982018

Related topics

Related topics

10 relations
Cell NucleusDNA-Binding ProteinsGenes, RegulatorMorphogenesis
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
SOX10 Transcription Factor
Cell Nucleus
Transcriptional Regulation
dna binding
Transcription Coactivator
Genes, Regulator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Sox10: a pan-schwannian and melanocytic marker.
S100 protein is a sensitive marker for melanomas and peripheral nerve sheath tumors. It is, however, expressed by other… (More)
  • table 1
  • table 3
  • table 2
  • figure 1
  • figure 2
Is this relevant?
2006
2006
Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence.
Sox8 and Sox10 are two closely related transcription factors of the Sox protein family with overlapping expression patterns… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2006
2006
Expression of connexin47 in oligodendrocytes is regulated by the Sox10 transcription factor.
In the central nervous system, Connexin32 and Connexin47 are confined to oligodendrocytes where they contribute to myelin… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy.
Development of myelin-forming oligodendrocytes in the central nervous system is dependent on at least two members of the Sox… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Human Connexin 32, a gap junction protein altered in the X-linked form of Charcot-Marie-Tooth disease, is directly regulated by the transcription factor SOX10.
Mutations in SOX10, a transcription modulator crucial in the development of the enteric nervous system (ENS), melanocytes and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Transcription factor hierarchy in Waardenburg syndrome: regulation of MITF expression by SOX10 and PAX3
Waardenburg syndrome (WS) is associated with neural crest-derived melanocyte deficiency caused by mutations in either one of… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Protein zero gene expression is regulated by the glial transcription factor Sox10.
Myelinating glia express high levels of a unique set of genes which code for structural proteins of the myelin sheath. Few… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Chick sox10, a transcription factor expressed in both early neural crest cells and central nervous system.
Human SOX10 and mouse Sox10 have been cloned and shown to be expressed in the neural crest derivatives that contribute to… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Sox10, a novel transcriptional modulator in glial cells.
Sox proteins are characterized by possession of a DNA-binding domain with similarity to the high-mobility group domain of the sex… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
1998
1998
The SOX10/Sox10 gene from human and mouse: sequence, expression, and transactivation by the encoded HMG domain transcription factor
The SOX genes form a gene family related by homology to the high-mobility group (HMG) box region of the testis-determining gene… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?