Skip to search form
Skip to main content
>
Semantic Scholar
Semantic Scholar's Logo
Search
Sign In
Create Free Account
You are currently offline. Some features of the site may not work correctly.
SOX10 Transcription Factor
Known as:
SOX 10 Transcription Factor
, Transcription Factor, SOX10
, SOX-10 Transcription Factor
Expand
Transcription factor SOX-10 (466 aa, ~50 kDa) is encoded by the human SOX10 gene. This protein is involved in the regulation of gene expression.
National Institutes of Health
Create Alert
Related topics
Related topics
11 relations
Cell Nucleus
DNA-Binding Proteins
Genes, Regulator
Morphogenesis
Expand
Broader (1)
SOXE Transcription Factors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
A novel group of spindle cell tumors defined by S100 and CD34 co‐expression shows recurrent fusions involving RAF1, BRAF, and NTRK1/2 genes
A. Suurmeijer
,
B. Dickson
,
+5 authors
C. Antonescu
Genes, chromosomes & cancer
2018
Corpus ID: 52899267
Tumors characterized by co‐expression of S100 and CD34, in the absence of SOX10, remain difficult to classify. Triggered by a few…
Expand
Highly Cited
2008
Highly Cited
2008
Sox10: A Pan-Schwannian and Melanocytic Marker
D. Nonaka
,
L. Chiriboga
,
B. Rubin
The American journal of surgical pathology
2008
Corpus ID: 25834573
S100 protein is a sensitive marker for melanomas and peripheral nerve sheath tumors. It is, however, expressed by other…
Expand
Highly Cited
2003
Highly Cited
2003
SOX10 Maintains Multipotency and Inhibits Neuronal Differentiation of Neural Crest Stem Cells
J. Kim
,
L. Lo
,
E. Dormand
,
D. Anderson
Neuron
2003
Corpus ID: 18623176
The mechanisms that establish and maintain the multipotency of stem cells are poorly understood. In neural crest stem cells…
Expand
Highly Cited
2002
Highly Cited
2002
Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10.
C. Stolt
,
S. Rehberg
,
+5 authors
M. Wegner
Genes & development
2002
Corpus ID: 7676923
Sox10 is a high-mobility-group transcriptional regulator in early neural crest. Without Sox10, no glia develop throughout the…
Expand
Highly Cited
2001
Highly Cited
2001
The transcription factor Sox10 is a key regulator of peripheral glial development.
S. Britsch
,
D. Goerich
,
+5 authors
M. Wegner
Genes & development
2001
Corpus ID: 13478338
The molecular mechanisms that determine glial cell fate in the vertebrate nervous system have not been elucidated. Peripheral…
Expand
Highly Cited
2000
Highly Cited
2000
Transcription factor hierarchy in Waardenburg syndrome: regulation of MITF expression by SOX10 and PAX3
S. B. Potterf
,
M. Furumura
,
K. Dunn
,
H. Arnheiter
,
W. Pavan
Human Genetics
2000
Corpus ID: 24931810
Abstract. Waardenburg syndrome (WS) is associated with neural crest-derived melanocyte deficiency caused by mutations in either…
Expand
Highly Cited
2000
Highly Cited
2000
Interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome.
N. Bondurand
,
V. Pingault
,
+5 authors
M. Goossens
Human molecular genetics
2000
Corpus ID: 7355937
Waardenburg syndrome (WS) is an autosomal dominant disorder with an incidence of 1 in 40 000 that manifests with sensorineural…
Expand
Highly Cited
1998
Highly Cited
1998
Sox10, a Novel Transcriptional Modulator in Glial Cells
K. Kuhlbrodt
,
B. Herbarth
,
E. Sock
,
I. Hermans-Borgmeyer
,
M. Wegner
The Journal of Neuroscience
1998
Corpus ID: 17780096
Sox proteins are characterized by possession of a DNA-binding domain with similarity to the high-mobility group domain of the sex…
Expand
Highly Cited
1998
Highly Cited
1998
SOX10 mutation disrupts neural crest development in Dom Hirschsprung mouse model
E. M. Southard-Smith
,
L. Kos
,
W. Pavan
Nature Genetics
1998
Corpus ID: 25574343
Hirschsprung disease (HSCR, MIM ♯142623) is a multigenic neuocristopathy (neural crest disorder) characterized by absence of…
Expand
Highly Cited
1998
Highly Cited
1998
SOX10 mutations in patients with Waardenburg-Hirschsprung disease
V. Pingault
,
N. Bondurand
,
+15 authors
M. Goossens
Nature Genetics
1998
Corpus ID: 2327032
Waardenburg syndrome (WS; deafness with pigmentary abnormalities) and Hirschsprung's disease (HSCR; aganglionic megacolon) are…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE