SORL1 gene

Known as: gp250, SORLA1, sortilin-related receptor, L(DLR class) A repeats containing 
This gene is involved in both endocytosis and protein sorting.
National Institutes of Health

Papers overview

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2015
2015
OBJECTIVE Common single nucleotide polymorphisms in the SORL1 gene have been associated with late onset Alzheimer disease (LOAD… (More)
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Highly Cited
2013
Highly Cited
2013
To discover susceptibility genes of late-onset Alzheimer's disease (LOAD), we conducted a 3-stage genome-wide association study… (More)
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Highly Cited
2012
Highly Cited
2012
Performing exome sequencing in 14 autosomal dominant early-onset Alzheimer disease (ADEOAD) index cases without mutation on known… (More)
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE To reexamine the association between the neuronal sortilin-related receptor gene (SORL1) and Alzheimer disease (AD… (More)
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2011
2011
BACKGROUND Recently, genetic variants of the neuronal sortilin-related receptor with A-type repeats (SORL1, also called LR11 or… (More)
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Highly Cited
2010
Highly Cited
2010
SorCS1 and SorL1/SorLA/LR11 belong to the sortilin family of vacuolar protein sorting-10 (Vps10) domain-containing proteins. Both… (More)
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2009
2009
Variations in sortilin-related receptor (SORL1) expression and function have been implicated in Alzheimers Disease (AD). Here, to… (More)
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2009
2009
Genetic variants of the neuronal sortilin-related receptor (SORL1) have been demonstrated to modulate the risk of Alzheimer's… (More)
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Highly Cited
2007
Highly Cited
2007
The recycling of the amyloid precursor protein (APP) from the cell surface via the endocytic pathways plays a key role in the… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To investigate the association between Alzheimer disease (AD) and variant alleles in SORL1 using a series of single… (More)
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