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SOD2 gene

Known as: MNSOD, superoxide dismutase 2, mitochondrial, SOD2 
This gene is involved in the detoxification of superoxide radicals produced within mitochondria.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS Mitochondria manganese… Expand
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Highly Cited
2010
Highly Cited
2010
A major cause of aging and numerous diseases is thought to be cumulative oxidative stress, resulting from the production of… Expand
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Highly Cited
2007
Highly Cited
2007
Mitochondrial damage is a well known cause of mitochondria-related diseases. A major mechanism underlying the development of… Expand
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Highly Cited
2007
Highly Cited
2007
PURPOSE To test the hypothesis that oxidative injury to the retinal pigment epithelium (RPE) may lead to retinal damage similar… Expand
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Highly Cited
2005
Highly Cited
2005
Oxidative stress may enhance prostatic carcinogenesis. A polymorphism [valine (V) --> alanine (A)] of manganese superoxide… Expand
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Highly Cited
2002
Highly Cited
2002
Oxidative stress has been widely implicated as an important factor in the aging process. Because mitochondrial respiration is the… Expand
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Highly Cited
2001
Highly Cited
2001
To determine the importance of mitochondrial reactive oxygen species toxicity in aging and senescence, we analyzed changes in… Expand
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Highly Cited
1998
Highly Cited
1998
This study characterizes mitochondria isolated from livers of Sod2 −/+ andSod2 +/+ mice. A 50% decrease in manganese superoxide… Expand
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Highly Cited
1996
Highly Cited
1996
Mitochondrial targeting sequence (MTS) has a common property to form an amphiphilic helical structure which is essential for its… Expand
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Highly Cited
1991
Highly Cited
1991
In plants, environmental adversity often leads to the formation of highly reactive oxygen radicals. Since resistance to such… Expand
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