SMG1 gene

Known as: KIAA0421, SMG1, ATX 
This gene is involved in protein phosphorylation, mRNA surveillance and genotoxic responses.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Autotaxin (ATX, also known as ectonucleotide pyrophosphatase/phosphodiesterase-2, ENPP2) is a secreted lysophospholipase D that… (More)
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2011
2011
Smac mimetic compounds (SMCs) are experimental small molecules that induce tumour necrosis factor alpha (TNFα)-dependent cancer… (More)
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Highly Cited
2010
Highly Cited
2010
Smg1 is a PI3K-related kinase (PIKK) associated with multiple cellular functions, including DNA damage responses, telomere… (More)
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Highly Cited
2010
Highly Cited
2010
TEL2 interacts with and is essential for the stability of all phosphatidylinositol 3-kinase-related kinases (PIKKs), but its… (More)
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Highly Cited
2008
Highly Cited
2008
Nonsense-mediated mRNA decay (NMD) represents a key mechanism to control the expression of wild-type and aberrant mRNAs… (More)
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Highly Cited
2006
Highly Cited
2006
The eukaryotic nonsense-mediated mRNA decay (NMD) pathway degrades mRNAs carrying premature stop codons (PTC). In humans, NMD… (More)
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Highly Cited
2005
Highly Cited
2005
Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that degrades mRNAs containing nonsense codons, and regulates the… (More)
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Highly Cited
2003
Highly Cited
2003
The nonsense-mediated mRNA decay (NMD) pathway promotes the rapid degradation of mRNAs containing premature stop codons (PTCs… (More)
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Highly Cited
2001
Highly Cited
2001
The HOG (high-osmolarity glycerol) mitogen-activated protein kinase (MAPK) pathway regulates the osmotic stress response in the… (More)
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1995
1995
BACKGROUND The mitogen-activated protein (MAP) kinase, ERK2, is a tightly regulated enzyme in the ubiquitous Ras-activated… (More)
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