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SMAD5 protein, human
Known as:
Mothers Against Decapentaplegic Homolog 5
, MAD Homolog 5
, SMA- and MAD-Related Protein 5
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Mothers against decapentaplegic homolog 5 (465 aa, ~52 kDa) is encoded by the human SMAD5 gene. This protein is involved in transcriptional…
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National Institutes of Health
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Related topics
Related topics
13 relations
BMP Receptor Signaling Pathway
DNA-Binding Proteins
Genes, Regulator
Pattern Formation
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Broader (1)
Smad5 Protein
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
MicroRNA-33 protects against neointimal hyperplasia induced by arterial mechanical stretch in the grafted vein
Kai Huang
,
H. Bao
,
+9 authors
Zong-Lai Jiang
Cardiovascular research
2017
Corpus ID: 3744595
Aims Mechanical factors play significant roles in neointimal hyperplasia after vein grafting, but the mechanisms are not fully…
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Highly Cited
2014
Highly Cited
2014
Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signaling
S. Tsukamoto
,
T. Mizuta
,
+9 authors
T. Katagiri
Scientific reports
2014
Corpus ID: 11450543
Smad1, Smad5 and Smad9 (also known as Smad8) are activated by phosphorylation by bone morphogenetic protein (BMP)-bound type I…
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Highly Cited
2011
Highly Cited
2011
Kaposi's Sarcoma-Associated Herpesvirus-Encoded MicroRNA miR-K12-11 Attenuates Transforming Growth Factor Beta Signaling through Suppression of SMAD5
Yunhua Liu
,
R. Sun
,
Xianzhi Lin
,
Deguang Liang
,
Q. Deng
,
K. Lan
Journal of Virology
2011
Corpus ID: 22181554
ABSTRACT Kaposi's sarcoma-associated herpesvirus (KSHV) encodes 12 pre-microRNAs (pre-miRNAs). Current studies have shown that…
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2011
2011
Dynamic analysis of BMP‐responsive smad activity in live zebrafish embryos
D. W. Laux
,
Jennifer A Febbo
,
B. L. Roman
Developmental dynamics : an official publication…
2011
Corpus ID: 689412
Bone morphogenetic proteins (BMPs) are critical players in development and disease, regulating such diverse processes as…
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Highly Cited
2007
Highly Cited
2007
Smad1 and Smad5 differentially regulate embryonic hematopoiesis.
L. J. McReynolds
,
Sunny Gupta
,
M. Figueroa
,
M. Mullins
,
T. Evans
Blood
2007
Corpus ID: 607482
The bone morphogenetic protein (BMP) signaling pathway regulates multiple steps of hematopoiesis, mediated through receptor…
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2003
2003
Generation of a floxed allele of Smad5 for cre‐mediated conditional knockout in the mouse
L. Umans
,
L. Vermeire
,
Annick Francis
,
H. Chang
,
D. Huylebroeck
,
A. Zwijsen
Genesis
2003
Corpus ID: 36412094
Summary: Smad5 is a member of the Smad family of intracellular mediators of BMP signals and in endothelial cells of TGF‐β signals…
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Highly Cited
2001
Highly Cited
2001
The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo.
H. Bauer
,
Z. Lele
,
G. Rauch
,
R. Geisler
,
M. Hammerschmidt
Development
2001
Corpus ID: 12290348
Ventral specification of mesoderm and ectoderm depends on signaling by members of the bone morphogenetic protein (Bmp) family…
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Highly Cited
1999
Highly Cited
1999
Smad1 and Smad5 have distinct roles during dorsoventral patterning of the zebrafish embryo
A. Dick
,
A. Meier
,
M. Hammerschmidt
Developmental dynamics : an official publication…
1999
Corpus ID: 13052808
smad1 and smad5 encode transcription factors that have been implicated in the transduction of signaling by the bone morphogenetic…
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1998
1998
hSmad5 gene, a human hSmad family member: its full length cDNA, genomic structure, promoter region and mutation analysis in human tumors
A. Gemma
,
K. Hagiwara
,
+5 authors
C. Harris
Oncogene
1998
Corpus ID: 31142581
hSmad (mothers against decapentaplegic)-related proteins are important messengers within the Transforming Growth Factor-β1 (TGF…
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Highly Cited
1997
Highly Cited
1997
Smad1 and smad5 act downstream of intracellular signalings of BMP-2 that inhibits myogenic differentiation and induces osteoblast differentiation in C2C12 myoblasts.
N. Yamamoto
,
S. Akiyama
,
T. Katagiri
,
M. Namiki
,
T. Kurokawa
,
T. Suda
Biochemical and biophysical research…
1997
Corpus ID: 967292
Bone morphogenetic protein-2 (BMP-2) inhibits terminal differentiation of C2C12 myoblasts and converts them into osteoblast…
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