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SMAD5 protein, human

Known as: Mothers Against Decapentaplegic Homolog 5, MAD Homolog 5, SMA- and MAD-Related Protein 5 
Mothers against decapentaplegic homolog 5 (465 aa, ~52 kDa) is encoded by the human SMAD5 gene. This protein is involved in transcriptional… 
National Institutes of Health

Related topics

Related topics

13 relations
BMP Receptor Signaling PathwayDNA-Binding ProteinsGenes, RegulatorPattern Formation

Broader (1)

Smad5 Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
BMP‐2 Induction of Dlx3 Expression Is Mediated by p38/Smad5 Signaling Pathway in Osteoblastic MC3T3‐E1 Cells
Dlx3 is essential for osteoblast differentiation and bone formation, and its expression is regulated by bone morphogenetic… 
Highly Cited
2011
Highly Cited
2011
Dynamic analysis of BMP‐responsive smad activity in live zebrafish embryos
Bone morphogenetic proteins (BMPs) are critical players in development and disease, regulating such diverse processes as… 
Review
2010
Review
2010
The role of Smad signaling in vascular and hematopoietic development revealed by studies using genetic mouse models
Smads are intracellular mediators of transforming growth factor β (TGF-β) superfamily signaling. In this review, we focus on the… 
2009
2009
"La scrittura cinematografica. Le categorie di genere fra cinema e letteratura: il caso Orlando".
Avvalendosi di strumenti teorici provenienti da differenti ambiti disciplinari quali la semiotica e la psicoanalisi, il presente… 
Highly Cited
2007
Highly Cited
2007
Smad1 and Smad5 differentially regulate embryonic hematopoiesis.
The bone morphogenetic protein (BMP) signaling pathway regulates multiple steps of hematopoiesis, mediated through receptor… 
2003
2003
Up-regulated Smad5 Mediates Apoptosis of Gastric Epithelial Cells Induced by Helicobacter pylori Infection*
The gastric pathogen Helicobacter pylori activates epithelial cell signaling pathways, and its infection induces changes in the… 
2003
2003
Inhalant nitrite exposure alters mouse hepatic angiogenic gene expression.
1999
1999
A maternal RNA encoding smad1/5 is segregated to animal blastomeres during ascidian development
Expressed Sequence Tag (EST) research on the ascidian Halocynthia roretzi revealed that Hrsmad1/5, a homolog of smad genes, is… 
1999
1999
An antisense transcript to SMAD5 expressed in fetal and tumor tissues.
SMAD5, a transducer of TGF-beta/BMP inhibitory signals and a tumor suppressor candidate, localizes to the region of invariant… 
1998
1998
hSmad5 gene, a human hSmad family member: its full length cDNA, genomic structure, promoter region and mutation analysis in human tumors
hSmad (mothers against decapentaplegic)-related proteins are important messengers within the Transforming Growth Factor-β1 (TGF… 
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