SMAD2 protein, human

Known as: SMA- and MAD-Related Protein 2, Mothers Against Decapentaplegic Homolog 2 Protein, Mothers Against DPP Homolog 2 
Mothers against decapentaplegic homolog 2 (467 aa, ~52 kDa) is encoded by the human SMAD2 gene. This protein plays a role in signal transduction and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Smad2 and Smad3 interact and mediate TGF-beta signaling. Although Smad3 promotes fibrosis, the role of Smad2 in fibrogenesis is… (More)
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Highly Cited
2009
Highly Cited
2009
TGF-beta induces phosphorylation of the transcription factors Smad2 and Smad3 at the C terminus as well as at an interdomain… (More)
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Review
2007
Review
2007
Transforming growth factor-beta (TGF-beta) is an important growth inhibitor of epithelial cells, and insensitivity to this… (More)
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Highly Cited
2005
Highly Cited
2005
MAN1 (also known as LEMD3) is an integral protein of the inner nuclear membrane. Recently, mutations in MAN1 have been shown to… (More)
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Highly Cited
2002
Highly Cited
2002
Metastasis is a multistep process that involves local tumour invasion followed by dissemination to, and re-establishment at… (More)
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Highly Cited
1998
Highly Cited
1998
Smads transmit signals from transmembrane ser/thr kinase receptors to the nucleus. We now identify SARA (for Smad anchor for… (More)
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Highly Cited
1998
Highly Cited
1998
Signalling by the transforming growth factor-β (TGF-β) superfamily of proteins depends on the phosphorylation and activation of… (More)
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Highly Cited
1998
Highly Cited
1998
smad genes constitute a family of nine members whose products serve as intracellular mediators of transforming growth factor beta… (More)
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Highly Cited
1997
Highly Cited
1997
Smad family members are newly identified essential intracellular signalling components of the transforming growth factor-beta… (More)
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Highly Cited
1997
Highly Cited
1997
Smad2 and Smad4 are related tumour-suppressor proteins, which, when stimulated by the growth factor TGF-β, form a complex to… (More)
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