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SLCO1B3 gene

Known as: solute carrier organic anion transporter family member 1B3, OATP8, SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY, MEMBER 1B3 
This gene plays a role in both the sodium-independent uptake of endogenous and xenobiotic compounds and the transport of bile acid and bilirubin.
National Institutes of Health

Related topics

Related topics

9 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
HUBUNGAN POLIMORFISME SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B1 (SLCO1B1) DAN 1B3 (SLCO1B3) DENGAN PROFIL FARMAKOKINETIK RIFAMPISIN PADA PENDERITA TUBERKULOSIS PARU INDONESIA
2016
2016
Counter-flow suggests transport of dantrolene and 5-OH dantrolene by the organic anion transporters 2 (OAT2) and 3 (OAT3)
Dantrolene is the only available drug for the treatment of malignant hyperthermia, a life-threatening inborn sensitivity of the… 
2015
2015
SLCO2B1 and SLCO1B3 as New Targets for Enhancing Androgen Deprivation Therapy for Prostate Cancer
Abstract : We found the association between the SLCO2B1 exonic SNP rs12422149 and time to progression(TTP) on ADT. We also found… 
2013
2013
Utility of Oatp 1 a / 1 b-Knockout and OATP 1 B 1 / 3-Humanized Mice in the Study of OATP-Mediated Pharmacokinetics and Tissue Distribution : Case Studies with Pravastatin , Atorvastatin…
Although organic anion transporting polypeptide (OATP)–mediated hepatic uptake is generally conserved between rodents and humans… 
2013
2013
Editors' pick 2012.
As in previous years, the editors have made a personal selection of some of what for us have been highlights among the papers… 
2012
2012
Predictive Biomarkers and Personalized Medicine In fl uence of Polymorphic OATP 1 B-Type Carriers on the Disposition of Docetaxel
Purpose:Docetaxel is extensivelymetabolized byCYP3A4 in the liver butmechanisms bywhich the drug is taken up into hepatocytes… 
2011
2011
transporter SLCO1B3 and the efflux transporter AB
2010
2010
Specific and general inhibitors of the three hepatic organic anion transporters OATP1B1 (SLCO1B1), OATP1B3 (SLCO1B3) and OATP2B1 (SLCO2B1)
Specific and general inhibitors of the three hepatic organic anion transporters OATP1B1 (SLCO1B1), OATP1B3 (SLCO1B3) and OATP2B1… 
2004
2004
Contribution of OATP 2 ( OATP 1 B 1 ) and OATP 8 ( OATP 1 B 3 ) to the Hepatic Uptake of Pitavastatin in Humans
Pitavastatin, a novel potent 3-hydroxymethylglutaryl-CoA reductase inhibitor, is selectively distributed to the liver in rats… 
1969
1969
Organic anion transport in mutant sheep with congenital hyperbilirubinemia.
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