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SLC6A3 protein, human

Known as: Solute Carrier Family 6 Member 3, Dopamine Transporter, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 protein, human 
Sodium-dependent dopamine transporter (620 aa, ~68 kDa) is encoded by the human SLC6A3 gene. This protein plays a role in the downregulation of… 
National Institutes of Health

Related topics

Related topics

13 relations
Cellular MembraneDAT1 protein, S cerevisiaeIntegral Membrane ProteinsLigand Binding

Broader (1)

dopamine transporter

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
DAT versus D2 receptor binding in the rat striatum: l‐DOPA‐induced motor activity is better predicted by reuptake than release of dopamine
The reuptake and release of dopamine (DA) can be estimated using in vivo imaging methods by assessing the competition between… 
2015
2015
Neonatal exposure to amphetamine alters social affiliation and central dopamine activity in adult male prairie voles
2014
2014
Selective Deletion of GRK2 Alters Psychostimulant-Induced Behaviors and Dopamine Neurotransmission
GRK2 is a G protein-coupled receptor kinase (GRK) that is broadly expressed and is known to regulate diverse types of receptors… 
2011
2011
meso-Transdiene Analogs Inhibit Vesicular Monoamine Transporter-2 Function and Methamphetamine-Evoked Dopamine Release
Lobeline, a nicotinic receptor antagonist and neurotransmitter transporter inhibitor, is a candidate pharmacotherapy for… 
2011
2011
Characterization of Pharmacological and Wake-Promoting Properties of the Dopaminergic Stimulant Sydnocarb in Rats
Sydnocarb is a psychomotor stimulant structurally similar to d-amphetamine (d-AMPH) and is used in Russia for the treatment of a… 
2005
2005
Involvement of dopamine receptors in cocaine-induced genital reflexes after paradoxical sleep deprivation
Highly Cited
2004
Highly Cited
2004
Nicotinic Receptor Modulation of Dopamine Transporter Function in Rat Striatum and Medial Prefrontal Cortex
Nicotine activates nicotinic acetylcholine receptors (nAChRs) on dopamine (DA) terminals to evoke DA release, which subsequently… 
2002
2002
Neurokinin Receptors Modulate the Neurochemical Actions of Cocaine
Abstract: The psychostimulant cocaine is an indirect agonist that increases synaptic dopamine (DA) by binding with high affinity… 
2001
2001
Antiproliferative action of dopamine and norepinephrine in neuroblastoma cells expressing the human dopamine transporter
The classical catecholamine transmitters dopamine and norepinephrine are also involved in neurodevelopment and neuron cell death… 
2000
2000
The zitter mutant rat exhibits loss of D3 receptors with degeneration of the dopamine system
Experimental studies of the regulation of the dopamine (DA) D3 receptor have utilized techniques causing massive depletions of… 
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