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SLC6A2 protein, human

Known as: Solute Carrier Family 6 Member 2, Norepinephrine Transporter, norepinephrine uptake-1 transporter, human 
Sodium-dependent noradrenaline transporter (617 aa, ~69 kDa) is encoded by the human SLC6A2 gene. This protein plays a role in the reuptake of… Expand
National Institutes of Health

Related topics

Related topics

15 relations
Cellular MembraneIntegral Membrane ProteinsLigand BindingMolecular Transport
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Broader (2)

Neurotransmitter Transport ProteinsNorepinephrine Plasma Membrane Transport Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homolog
Neurotransmitter/Na+ symporters (NSSs) terminate neuronal signalling by recapturing neurotransmitter released into the synapse in… Expand
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Highly Cited
2010
Highly Cited
2010
Single-molecule dynamics of gating in a neurotransmitter transporter homolog
Neurotransmitter:Na+ symporters (NSS) remove neurotransmitters from the synapse in a reuptake process that is driven by the Na… Expand
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Highly Cited
2005
Highly Cited
2005
Targeted gene expression in dopamine and serotonin neurons of the mouse brain
We used a knock-in strategy to generate two lines of mice expressing Cre recombinase under the transcriptional control of the… Expand
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Highly Cited
2005
Highly Cited
2005
Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
Neurotransmitter transporters are critical for synaptic neurotransmitter inactivation. Transporter inhibitors markedly increase… Expand
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Review
2004
Review
2004
Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6
The SLC6 family is a diverse set of transporters that mediate solute translocation across cell plasma membranes by coupling… Expand
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Highly Cited
2004
Highly Cited
2004
Two Discontinuous Segments in the Carboxyl Terminus Are Required for Membrane Targeting of the Rat γ-Aminobutyric Acid Transporter-1 (GAT1)*
Like all members of the Na+/Cl--dependent neurotransmitter transporter family, the rat γ-aminobutyric acid transporter-1 (GAT1… Expand
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Highly Cited
2004
Highly Cited
2004
Molecular Cloning of Mouse Amino Acid Transport System B0, a Neutral Amino Acid Transporter Related to Hartnup Disorder*
Resorption of amino acids in kidney and intestine is mediated by transporters, which prefer groups of amino acids with similar… Expand
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Highly Cited
1999
Highly Cited
1999
Molecular Analysis of System N Suggests Novel Physiological Roles in Nitrogen Metabolism and Synaptic Transmission
The amino acid glutamine has a central role in nitrogen metabolism. Although the molecular mechanisms responsible for its… Expand
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Highly Cited
1993
Highly Cited
1993
Phosphorylation and modulation of brain glutamate transporters by protein kinase C.
High affinity sodium- and potassium-coupled L-glutamate transport into presynaptic nerve terminals and fine glial processes… Expand
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Highly Cited
1991
Highly Cited
1991
Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter
AT most synapses, chemical signalling is terminated by a rapid reaccumulation of neurotransmitter into presynaptic terminals1–5… Expand
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