SLC6A2 protein, human

Known as: Solute Carrier Family 6 Member 2, Norepinephrine Transporter, norepinephrine uptake-1 transporter, human 
Sodium-dependent noradrenaline transporter (617 aa, ~69 kDa) is encoded by the human SLC6A2 gene. This protein plays a role in the reuptake of… (More)
National Institutes of Health

Related topics

Related topics

15 relations
Cellular MembraneIntegral Membrane ProteinsLigand BindingMolecular Transport
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Broader (2)

Neurotransmitter Transport ProteinsNorepinephrine Plasma Membrane Transport Proteins

Papers overview

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Highly Cited
2011
Highly Cited
2011
Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homolog
Neurotransmitter/Na+ symporters (NSSs) terminate neuronal signalling by recapturing neurotransmitter released into the synapse in… (More)
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Highly Cited
2010
Highly Cited
2010
Single-molecule dynamics of gating in a neurotransmitter transporter homolog
Neurotransmitter:Na+ symporters (NSS) remove neurotransmitters from the synapse in a reuptake process that is driven by the Na… (More)
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Review
2006
Review
2006
The SLC6 orphans are forming a family of amino acid transporters
Transporters in the human genome are grouped in solute carrier families (SLC). The SLC6 family is one of the biggest transporter… (More)
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Highly Cited
2005
Highly Cited
2005
Targeted gene expression in dopamine and serotonin neurons of the mouse brain
We used a knock-in strategy to generate two lines of mice expressing Cre recombinase under the transcriptional control of the… (More)
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Highly Cited
2005
Highly Cited
2005
Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
Neurotransmitter transporters are critical for synaptic neurotransmitter inactivation. Transporter inhibitors markedly increase… (More)
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Highly Cited
2003
Highly Cited
2003
Vesicular neurotransmitter transporter expression in developing postnatal rodent retina: GABA and glycine precede glutamate.
Vesicular transporters regulate the amount and type of neurotransmitter sequestered into synaptic vesicles and, hence, the kind… (More)
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2001
2001
Calcium- and syntaxin 1-mediated trafficking of the neuronal glycine transporter GLYT2.
Previously we demonstrated the existence of a physical and functional interaction between the glycine transporters and the SNARE… (More)
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Highly Cited
1999
Highly Cited
1999
Molecular Analysis of System N Suggests Novel Physiological Roles in Nitrogen Metabolism and Synaptic Transmission
The amino acid glutamine has a central role in nitrogen metabolism. Although the molecular mechanisms responsible for its… (More)
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Highly Cited
1993
Highly Cited
1993
Phosphorylation and modulation of brain glutamate transporters by protein kinase C.
High affinity sodium- and potassium-coupled L-glutamate transport into presynaptic nerve terminals and fine glial processes… (More)
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Highly Cited
1991
Highly Cited
1991
Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter
AT most synapses, chemical signalling is terminated by a rapid reaccumulation of neurotransmitter into presynaptic terminals1–5… (More)
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