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SLC6A2 protein, human
Known as:
Solute Carrier Family 6 Member 2
, Norepinephrine Transporter
, norepinephrine uptake-1 transporter, human
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Sodium-dependent noradrenaline transporter (617 aa, ~69 kDa) is encoded by the human SLC6A2 gene. This protein plays a role in the reuptake of…
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National Institutes of Health
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Related topics
Related topics
15 relations
Cellular Membrane
Integral Membrane Proteins
Ligand Binding
Molecular Transport
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Broader (2)
Neurotransmitter Transport Proteins
Norepinephrine Plasma Membrane Transport Proteins
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homolog
Yongfang Zhao
,
Daniel S. Terry
,
+4 authors
J. Javitch
Nature
2011
Corpus ID: 4404201
Neurotransmitter/Na+ symporters (NSSs) terminate neuronal signalling by recapturing neurotransmitter released into the synapse in…
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Highly Cited
2010
Highly Cited
2010
Single-molecule dynamics of gating in a neurotransmitter transporter homolog
Yongfang Zhao
,
Daniel S. Terry
,
Lei Shi
,
H. Weinstein
,
S. Blanchard
,
J. Javitch
Nature
2010
Corpus ID: 4360313
Neurotransmitter:Na+ symporters (NSS) remove neurotransmitters from the synapse in a reuptake process that is driven by the Na…
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Highly Cited
2006
Highly Cited
2006
A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder
Chun-Hyung Kim
,
M. K. Hahn
,
+10 authors
Kwang-Soo Kim
Proceedings of the National Academy of Sciences
2006
Corpus ID: 12476886
The norepinephrine transporter critically regulates both neurotransmission and homeostasis of norepinephrine in the nervous…
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Highly Cited
2005
Highly Cited
2005
Targeted gene expression in dopamine and serotonin neurons of the mouse brain
X. Zhuang
,
J. Masson
,
J. Gingrich
,
S. Rayport
,
R. Hen
Journal of Neuroscience Methods
2005
Corpus ID: 7570157
Highly Cited
2005
Highly Cited
2005
Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
Katherine Holton
,
M. Loder
,
H. Melikian
Nature Neuroscience
2005
Corpus ID: 21130815
Neurotransmitter transporters are critical for synaptic neurotransmitter inactivation. Transporter inhibitors markedly increase…
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Review
2004
Review
2004
Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6
N. Chen
,
M. Reith
,
M. Quick
Pflügers Archiv
2004
Corpus ID: 34991320
The SLC6 family is a diverse set of transporters that mediate solute translocation across cell plasma membranes by coupling…
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Highly Cited
2004
Highly Cited
2004
Molecular Cloning of Mouse Amino Acid Transport System B0, a Neutral Amino Acid Transporter Related to Hartnup Disorder*
A. Bröer
,
K. Klingel
,
S. Kowalczuk
,
J. Rasko
,
J. Cavanaugh
,
S. Bröer
Journal of Biological Chemistry
2004
Corpus ID: 23918669
Resorption of amino acids in kidney and intestine is mediated by transporters, which prefer groups of amino acids with similar…
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Highly Cited
1999
Highly Cited
1999
Molecular Analysis of System N Suggests Novel Physiological Roles in Nitrogen Metabolism and Synaptic Transmission
F. Chaudhry
,
R. Reimer
,
+4 authors
R. Edwards
Cell
1999
Corpus ID: 17639583
Highly Cited
1993
Highly Cited
1993
Phosphorylation and modulation of brain glutamate transporters by protein kinase C.
M. Casado
,
A. Bendahan
,
+4 authors
B. Kanner
Journal of Biological Chemistry
1993
Corpus ID: 39552205
Highly Cited
1991
Highly Cited
1991
Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter
T. Pacholczyk
,
R. Blakely
,
S. Amara
Nature
1991
Corpus ID: 4333895
AT most synapses, chemical signalling is terminated by a rapid reaccumulation of neurotransmitter into presynaptic terminals1–5…
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