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SLC6A2 protein, human

Known as: Solute Carrier Family 6 Member 2, Norepinephrine Transporter, norepinephrine uptake-1 transporter, human 
Sodium-dependent noradrenaline transporter (617 aa, ~69 kDa) is encoded by the human SLC6A2 gene. This protein plays a role in the reuptake of… 
National Institutes of Health

Related topics

Related topics

15 relations
Cellular MembraneIntegral Membrane ProteinsLigand BindingMolecular Transport

Broader (2)

Neurotransmitter Transport ProteinsNorepinephrine Plasma Membrane Transport Proteins

Papers overview

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Highly Cited
2011
Highly Cited
2011
Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homolog
Neurotransmitter/Na+ symporters (NSSs) terminate neuronal signalling by recapturing neurotransmitter released into the synapse in… 
Highly Cited
2010
Highly Cited
2010
Single-molecule dynamics of gating in a neurotransmitter transporter homolog
Neurotransmitter:Na+ symporters (NSS) remove neurotransmitters from the synapse in a reuptake process that is driven by the Na… 
Highly Cited
2006
Highly Cited
2006
A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder
The norepinephrine transporter critically regulates both neurotransmission and homeostasis of norepinephrine in the nervous… 
Highly Cited
2005
Highly Cited
2005
Targeted gene expression in dopamine and serotonin neurons of the mouse brain
Highly Cited
2005
Highly Cited
2005
Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
Neurotransmitter transporters are critical for synaptic neurotransmitter inactivation. Transporter inhibitors markedly increase… 
Review
2004
Review
2004
Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6
The SLC6 family is a diverse set of transporters that mediate solute translocation across cell plasma membranes by coupling… 
Highly Cited
2004
Highly Cited
2004
Molecular Cloning of Mouse Amino Acid Transport System B0, a Neutral Amino Acid Transporter Related to Hartnup Disorder*
Resorption of amino acids in kidney and intestine is mediated by transporters, which prefer groups of amino acids with similar… 
Highly Cited
1999
Highly Cited
1999
Molecular Analysis of System N Suggests Novel Physiological Roles in Nitrogen Metabolism and Synaptic Transmission
Highly Cited
1993
Highly Cited
1993
Phosphorylation and modulation of brain glutamate transporters by protein kinase C.
Highly Cited
1991
Highly Cited
1991
Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter
AT most synapses, chemical signalling is terminated by a rapid reaccumulation of neurotransmitter into presynaptic terminals1–5… 
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