SLC5A2 wt Allele

Known as: SGLT2, Solute Carrier Family 5 (Sodium/Glucose Cotransporter), Member 2 wt Allele, Sodium-Glucose Cotransporter, Kidney Low Affinity Gene 
Human SLC5A2 wild-type allele is located in the vicinity of 16p11.2 and is approximately 8 kb in length. This allele, which encodes sodium/glucose… (More)
National Institutes of Health

Papers overview

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Review
2015
Review
2015
CONTEXT Sodium glucose cotransporter 2 (SGLT2) inhibitors are antidiabetic drugs that increase urinary excretion of glucose… (More)
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Highly Cited
2014
Highly Cited
2014
Our previous work has shown that gene knockout of the sodium-glucose cotransporter SGLT2 modestly lowered blood glucose in… (More)
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Review
2014
Review
2014
The importance of the kidney's role in glucose homeostasis has gained wider understanding in recent years. Consequently, the… (More)
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Highly Cited
2013
Highly Cited
2013
The Na-glucose cotransporter SGLT2 mediates high-capacity glucose uptake in the early proximal tubule and SGLT2 inhibitors are… (More)
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE Inhibition of the Na(+)-glucose cotransporter type 2 (SGLT2) is currently being pursued as an insulin-independent… (More)
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Review
2010
Review
2010
Inhibiting sodium–glucose co-transporters (SGLTs), which have a key role in the reabsorption of glucose in the kidney, has been… (More)
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Review
2010
Review
2010
CONTEXT Sodium-glucose cotransporter 2 (SGLT2) expressed in the proximal renal tubules accounts for about 90% of the reabsorption… (More)
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Highly Cited
2009
Highly Cited
2009
Dapagliflozin selectively inhibits renal glucose reabsorption by inhibiting sodium-glucose cotransporter-2 (SGLT2). It was… (More)
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Highly Cited
2008
Highly Cited
2008
Mutations in Na(+)-glucose transporters (SGLT)-2 and hepatocyte nuclear factor (HNF)-1alpha genes have been related to renal… (More)
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Highly Cited
2006
Highly Cited
2006
The low-affinity sodium glucose cotransporter (SGLT2), which is expressed specifically in the kidney, plays a major role in renal… (More)
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