Skip to search formSkip to main contentSkip to account menu

SLC39A6 wt Allele

Known as: LIV1, Solute Carrier Family 39 (Metal Ion Transporter), Member 6 Gene, Solute Carrier Family 39 (Zinc Transporter), Member 6 wt Allele 
Human SLC39A6 wild-type allele is located in the vicinity of 18q12.2 and is approximately 21 kb in length. This allele, which encodes zinc… 
National Institutes of Health

Related topics

Related topics

5 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract P6-12-04: Phase 1 study of the antibody-drug conjugate (ADC) SGN-LIV1A in patients with heavily pretreated metastatic breast cancer
Background LIV-1, a transmembrane protein and downstream target of STAT3, is highly expressed in breast cancer cells. It is… 
2016
2016
Zinc transporter ZIP 10 forms a heteromer with ZIP 6 which regulates embryonic development and cell migration
Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration Kathryn M. Taylor*1… 
2016
2016
Abstract 2966: Preclinical combinations of the antibody-drug conjugate SGN-LIV1A with chemotherapies show increased activity
SGN-LIV1A is an antibody-drug conjugate (ADC) currently being evaluated in a phase 1 clinical trial for metastatic breast cancer… 
2015
2015
Effect of LIV1 on the sensitivity of ovarian cancer cells to trichostatin A.
In a previous study, we used a functional gene screen approach to identify the key genes responsible for the tumor-selective… 
2014
2014
The zinc transporter LIV-1 is a novel regulator of stemness in pancreatic cancer cells
Abstract Objective. Recent studies have identified the existence a portion of cancer cells, called “cancer stem cells”, within… 
2013
2013
Negative Correlation of LIV-1 and E-Cadherin Expression in Hepatocellular Carcinoma Cells
LIV-1, a zinc transporter, is a mediator downstream of STAT3 both in zebrafish and mammalian cells, and is involved in epithelial… 
2008
2008
LIV-1 and Zn Transporters: Establishing a Link Between Hyperprolactinemia and Breast Cancer
Abstract : Evidence implicates dysregulated cellular zinc (Zn) metabolism in breast cancer. Regulation of Zn transport controls… 
2007
2007
[Expression of LIV-1 mRNA in human cervical carcinoma and endometrial carcinoma].
OBJECTIVE To investigate the mRNA expression of oestrogen-regulated gene LIV-1 in human cervical carcinoma and endometrial… 
1996
1996
Interaction between estradiol and cAMP in the regulation of specific gene expression
1996
1996
Oestrogen and insulin interact at the level of transcription in breast cancer cells.
‘the growth of the human breast cancer cell line, MCF-7, is stimulated by oestrogen and inhibited by antioestrogens both in vitro… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)