SLC39A6 wt Allele

Known as: LIV1, Solute Carrier Family 39 (Metal Ion Transporter), Member 6 Gene, Solute Carrier Family 39 (Zinc Transporter), Member 6 wt Allele 
Human SLC39A6 wild-type allele is located in the vicinity of 18q12.2 and is approximately 21 kb in length. This allele, which encodes zinc… (More)
National Institutes of Health

Related topics

Related topics

5 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport
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Papers overview

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2011
2011
Regulation of T cell receptor signaling by activation-induced zinc influx
Zinc is a trace element that is essential for innate and adaptive immune responses. In addition to being a structural element of… (More)
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Highly Cited
2011
Highly Cited
2011
LIV-1 Promotes Prostate Cancer Epithelial-to-Mesenchymal Transition and Metastasis through HB-EGF Shedding and EGFR-Mediated ERK Signaling
LIV-1, a zinc transporter, is an effector molecule downstream from soluble growth factors. This protein has been shown to promote… (More)
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Review
2009
Review
2009
Mammalian zinc transporters: nutritional and physiologic regulation.
Research advances defining how zinc is transported into and out of cells and organelles have increased exponentially within the… (More)
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2009
2009
Evolutionary Descent of Prion Genes from the ZIP Family of Metal Ion Transporters
In the more than twenty years since its discovery, both the phylogenetic origin and cellular function of the prion protein (PrP… (More)
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2008
2008
A distinct role in breast cancer for two LIV-1 family zinc transporters.
Zinc, essential for normal cell growth, is tightly controlled in cells by two families of zinc transporters. The aberrant… (More)
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Highly Cited
2005
Highly Cited
2005
Structure-function analysis of a novel member of the LIV-1 subfamily of zinc transporters, ZIP14.
Here, we report the first investigation of a novel member of the LZT (LIV-1 subfamily of ZIP zinc Transporters) subfamily of zinc… (More)
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2005
2005
Expression levels of the putative zinc transporter LIV-1 are associated with a better outcome of breast cancer patients.
We investigated the expression pattern of the breast cancer associated gene LIV-1 on mRNA and protein level in 111 human breast… (More)
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Highly Cited
2004
Highly Cited
2004
Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer
Vertebrate gastrulation is a critical step in the establishment of body plan. During gastrulation, epithelial-mesenchymal… (More)
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Review
2003
Review
2003
The LZT proteins; the LIV-1 subfamily of zinc transporters.
Zinc is an essential ion for cells with a vital role to play in controlling the cellular processes of the cell, such as growth… (More)
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Highly Cited
2003
Highly Cited
2003
Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters.
The LIV-1 gene has been previously associated with oestrogen-positive breast cancer and its metastatic spread to the regional… (More)
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