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SLC39A6 wt Allele
Known as:
LIV1
, Solute Carrier Family 39 (Metal Ion Transporter), Member 6 Gene
, Solute Carrier Family 39 (Zinc Transporter), Member 6 wt Allele
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Human SLC39A6 wild-type allele is located in the vicinity of 18q12.2 and is approximately 21 kb in length. This allele, which encodes zinc…
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National Institutes of Health
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Related topics
Related topics
5 relations
Homo sapiens
Ionophore activity
Ligand Binding
Molecular Transport
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract P6-12-04: Phase 1 study of the antibody-drug conjugate (ADC) SGN-LIV1A in patients with heavily pretreated metastatic breast cancer
A. Forero-Torres
,
S. Modi
,
+9 authors
M. Mita
2017
Corpus ID: 79356248
Background LIV-1, a transmembrane protein and downstream target of STAT3, is highly expressed in breast cancer cells. It is…
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2016
2016
Zinc transporter ZIP 10 forms a heteromer with ZIP 6 which regulates embryonic development and cell migration
K. Taylor
,
I. Muraina
,
+5 authors
C. Hogstrand
2016
Corpus ID: 43377800
Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration Kathryn M. Taylor*1…
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2016
2016
Abstract 2966: Preclinical combinations of the antibody-drug conjugate SGN-LIV1A with chemotherapies show increased activity
Fu Li
,
Martha E. Anderson
,
+5 authors
D. Sussman
2016
Corpus ID: 79134696
SGN-LIV1A is an antibody-drug conjugate (ADC) currently being evaluated in a phase 1 clinical trial for metastatic breast cancer…
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2015
2015
Effect of LIV1 on the sensitivity of ovarian cancer cells to trichostatin A.
Xiaoli Ma
,
Huayan Duan
,
+4 authors
Jiandong Wang
Oncology Report
2015
Corpus ID: 18327422
In a previous study, we used a functional gene screen approach to identify the key genes responsible for the tumor-selective…
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2014
2014
The zinc transporter LIV-1 is a novel regulator of stemness in pancreatic cancer cells
J. Unno
,
A. Masamune
,
S. Hamada
,
T. Shimosegawa
Scandinavian Journal of Gastroenterology
2014
Corpus ID: 21867249
Abstract Objective. Recent studies have identified the existence a portion of cancer cells, called “cancer stem cells”, within…
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2013
2013
Negative Correlation of LIV-1 and E-Cadherin Expression in Hepatocellular Carcinoma Cells
Rongxi Shen
,
Feng Xie
,
+5 authors
Jiamei Yang
PLoS ONE
2013
Corpus ID: 17820612
LIV-1, a zinc transporter, is a mediator downstream of STAT3 both in zebrafish and mammalian cells, and is involved in epithelial…
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2008
2008
LIV-1 and Zn Transporters: Establishing a Link Between Hyperprolactinemia and Breast Cancer
S. Kelleher
,
V. López
2008
Corpus ID: 53444314
Abstract : Evidence implicates dysregulated cellular zinc (Zn) metabolism in breast cancer. Regulation of Zn transport controls…
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2007
2007
[Expression of LIV-1 mRNA in human cervical carcinoma and endometrial carcinoma].
Le Zhao
,
Wei Chen
,
Xu Li
Nan fang yi ke da xue xue bao = Journal of…
2007
Corpus ID: 42447283
OBJECTIVE To investigate the mRNA expression of oestrogen-regulated gene LIV-1 in human cervical carcinoma and endometrial…
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1996
1996
Interaction between estradiol and cAMP in the regulation of specific gene expression
M. K. El-Tanani
,
C. Green
Molecular and Cellular Endocrinology
1996
Corpus ID: 37554779
1996
1996
Oestrogen and insulin interact at the level of transcription in breast cancer cells.
M. K. El-Tanani
,
C. Green
Biochemical Society Transactions
1996
Corpus ID: 41998598
‘the growth of the human breast cancer cell line, MCF-7, is stimulated by oestrogen and inhibited by antioestrogens both in vitro…
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