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SLC39A6 wt Allele

Known as: LIV1, Solute Carrier Family 39 (Metal Ion Transporter), Member 6 Gene, Solute Carrier Family 39 (Zinc Transporter), Member 6 wt Allele 
Human SLC39A6 wild-type allele is located in the vicinity of 18q12.2 and is approximately 21 kb in length. This allele, which encodes zinc… Expand
National Institutes of Health

Related topics

Related topics

5 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells
Background: Zinc influx transporters (ZIPs), together with zinc efflux transporters (ZnTs), regulate cellular zinc homeostasis… Expand
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Highly Cited
2011
Highly Cited
2011
Regulation of T cell receptor signaling by activation-induced zinc influx
Zinc enhances TCR signaling in part by inhibiting Shp-1 recruitment to the TCR synapse. 
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Highly Cited
2010
Highly Cited
2010
Zip6-attenuation promotes epithelial-to-mesenchymal transition in ductal breast tumor (T47D) cells.
Breast cancer is associated with zinc (Zn) hyper-accumulation in breast tissue which is postulated to be potentiated by the over… Expand
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Review
2009
Review
2009
Mammalian zinc transporters: nutritional and physiologic regulation.
Research advances defining how zinc is transported into and out of cells and organelles have increased exponentially within the… Expand
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Highly Cited
2009
Highly Cited
2009
SLC39A9 (ZIP9) Regulates Zinc Homeostasis in the Secretory Pathway: Characterization of the ZIP Subfamily I Protein in Vertebrate Cells
The SLC39A family of zinc transporters can be divided into four subfamilies (I, II, LIV-1, and gufA) in vertebrates, but studies… Expand
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Highly Cited
2006
Highly Cited
2006
Toll-like receptor–mediated regulation of zinc homeostasis influences dendritic cell function
Zinc is a trace element that is essential for the function of many enzymes and transcription factors. Zinc deficiency results in… Expand
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Highly Cited
2005
Highly Cited
2005
Structure–function analysis of a novel member of the LIV‐1 subfamily of zinc transporters, ZIP14
Here, we report the first investigation of a novel member of the LZT (LIV‐1 subfamily of ZIP zinc Transporters) subfamily of zinc… Expand
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Highly Cited
2004
Highly Cited
2004
Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer
Vertebrate gastrulation is a critical step in the establishment of body plan. During gastrulation, epithelial-mesenchymal… Expand
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Review
2003
Review
2003
The LZT proteins; the LIV-1 subfamily of zinc transporters.
Zinc is an essential ion for cells with a vital role to play in controlling the cellular processes of the cell, such as growth… Expand
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Highly Cited
2003
Highly Cited
2003
Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters.
The LIV-1 gene has been previously associated with oestrogen-positive breast cancer and its metastatic spread to the regional… Expand
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