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High fat diet (HFD)-induced obesity has been shown to reduce the levels of neuronal plasticity-related proteins, specifically… Expand Background: Genetic mutations in cancer-driver genes induce specific metabolic alterations in cancer cells. Results: EGF receptor… Expand PURPOSE
The usefulness of 2-[(18)F]-fluoro-2-deoxy-D-glucose ([(18)F]FDG) positron emission tomography (PET) can help predict the… Expand Glioblastoma (GBM) is the most frequent malignant glioma. Treatment of GBM patients is multimodal with maximum surgical resection… Expand Ischemic and excitotoxic events within the brain result in rapid and often unfavorable depletions in neuronal energy levels. Here… Expand HIF-1alpha plays an indispensable role in tumor formation and histogenesis. Target genes involved in glucose transport are… Expand Abstract Fetal macronutrient requirements for oxidative metabolism and growth are met by placental transport of glucose, amino… Expand Traumatic brain injury results in an increased brain energy demand that is associated with profound changes in brain glycolysis… Expand Insulin activates certain protein kinase C (PKC) isoforms that are involved in insulin-induced glucose transport. In this study… Expand Positron emission tomography (PET) studies measuring glucose utilization have demonstrated cerebral hypometabolism in Alzheimer's… Expand