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SLC26A6 gene

Known as: anion transporter 1, solute carrier family 26 member 6, SLC26A6 
This gene is involved in acid-base homeostasis.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Transcellular Cl(-) and HCO(3)(-) transport is a vital function of secretory epithelia and exit across the luminal membrane is… Expand
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Highly Cited
2006
Highly Cited
2006
Urolithiasis is one of the most common urologic diseases in industrialized societies. Calcium oxalate is the predominant… Expand
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Highly Cited
2005
Highly Cited
2005
SLC26A6 (PAT1, CFEX) is an anion exchanger that is expressed on the apical membrane of the kidney proximal tubule and the small… Expand
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Highly Cited
2004
Highly Cited
2004
Chloride absorption and bicarbonate secretion are vital functions of epithelia, as highlighted by cystic fibrosis and diseases… Expand
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Review
2004
Review
2004
The ten-member SLC26 gene family encodes anion exchangers capable of transporting a wide variety of monovalent and divalent… Expand
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Highly Cited
2004
Highly Cited
2004
Mutations in the serine-threonine kinase WNK4 [with no lysine (K) 4] cause pseudohypoaldosteronism type II, a Mendelian disease… Expand
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Highly Cited
2002
Highly Cited
2002
Aberrant HCO(3)(-) transport is a hallmark of cystic fibrosis (CF) and is associated with aberrant Cl(-)-dependent HCO(3… Expand
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Highly Cited
2002
Highly Cited
2002
HCO3(-) secretion is the most important defense mechanism against acid injury in the duodenum. However, the identity of the… Expand
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Highly Cited
2001
Highly Cited
2001
A key function of the proximal tubule is retrieval of most of the vast quantities of NaCl and water filtered by the kidney… Expand
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Highly Cited
1999
Highly Cited
1999
Nephrotoxicity is the dose-limiting clinical adverse effect of cidofovir and adefovir, two potent antiviral therapeutics. Because… Expand
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