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SLC22A1 wt Allele

Known as: HOCT1, Solute Carrier Family 22 (Organic Cation Transporter), Member 1 wt Allele, OCT1 
Human SLC22A1 wild-type allele is located in the vicinity of 6q25.3 and is approximately 37 kb in length. This allele, which encodes solute carrier… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Some chronic myeloid leukemia (CML) patients do not respond to imatinib, whereas others lose an initial response. To identify… Expand
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Highly Cited
2005
Highly Cited
2005
This study was performed to investigate which human organic cation transporter, hOCT1, hOCT2 or hOCT3, participates with regard… Expand
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Highly Cited
2004
Highly Cited
2004
Imatinib is a tyrosine kinase inhibitor that is effective in the treatment of chronic myeloid leukemia (CML). Not all patients… Expand
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Highly Cited
2002
Highly Cited
2002
Renal excretion of organic anions and cations is mediated by the organic ion transporter family (SLC22A). In this study, the mRNA… Expand
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Highly Cited
2002
Highly Cited
2002
Organic cation transporters (OCTs) are involved in the elimination of monoamines and cationic xenobiotics. To examine whether… Expand
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Highly Cited
2002
Highly Cited
2002
Renal excretion is an important elimination pathway for antiviral agents, such as acyclovir (ACV), ganciclovir (GCV), and… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT The polyspecific organic cation transporter 1 (OCT1 [SLC22A1]) mediates facilitated transport of small (hydrophilic… Expand
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Highly Cited
1998
Highly Cited
1998
Recently, a polyspecific organic cation transporter, hOCT1, was cloned from human liver. To date, limited studies examining the… Expand
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Highly Cited
1997
Highly Cited
1997
Previously we cloned a polyspecific transporter from rat (rOCT1) that is expressed in renal proximal tubules and hepatocytes and… Expand
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Highly Cited
1997
Highly Cited
1997
Polyspecific organic cation transporters in the liver mediate the elimination of a wide array of endogenous amines and… Expand
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