SLC22A1 wt Allele

Known as: HOCT1, Solute Carrier Family 22 (Organic Cation Transporter), Member 1 wt Allele, OCT1 
Human SLC22A1 wild-type allele is located in the vicinity of 6q25.3 and is approximately 37 kb in length. This allele, which encodes solute carrier… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Some chronic myeloid leukemia (CML) patients do not respond to imatinib, whereas others lose an initial response. To identify… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Metformin is a widely used oral antihyperglycemic drug for the treatment of type II diabetes mellitus. The intestinal absorption… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
This study was performed to investigate which human organic cation transporter, hOCT1, hOCT2 or hOCT3, participates with regard… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Imatinib is a tyrosine kinase inhibitor that is effective in the treatment of chronic myeloid leukemia (CML). Not all patients… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Renal excretion of organic anions and cations is mediated by the organic ion transporter family (SLC22A). In this study, the mRNA… (More)
  • table 1
  • table 2
  • figure 2
  • figure 1
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
1. Organic cation transporters (OCTs) are involved in the elimination of monoamines and cationic xenobiotics. To examine whether… (More)
  • figure 2
  • figure 1
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The purpose of this study was to elucidate the interactions of human organic anion transporters (hOATs) and human organic cation… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The polyspecific organic cation transporter 1 (OCT1 [SLC22A1]) mediates facilitated transport of small (hydrophilic) organic… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Previously we cloned a polyspecific transporter from rat (rOCT1) that is expressed in renal proximal tubules and hepatocytes and… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Polyspecific organic cation transporters in the liver mediate the elimination of a wide array of endogenous amines and… (More)
  • table 1
  • figure 2
  • figure 1
  • figure 3
  • table 2
Is this relevant?