SIRPA wt Allele

Known as: PTPNS1, Protein-Tyrosine Phosphatase, Nonreceptor Type, Substrate 1 Gene, Macrophage Fusion Receptor Gene 
Human SIRPA wild-type allele is located within 20p13 and is approximately 45 kb in length. This allele, which encodes tyrosine-protein phosphatase… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Macrophages clear pathogens and damaged or aged cells from the blood stream via phagocytosis. Cell-surface CD47 interacts with… (More)
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Review
2009
Review
2009
Signal regulatory protein (SIRP)alpha, also known as SHPS-1 or SIRPA, is a transmembrane protein that binds to the protein… (More)
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Highly Cited
2007
Highly Cited
2007
We have previously proven that human macrophages can phagocytose porcine cells even in the absence of Ab or complement… (More)
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Highly Cited
2005
Highly Cited
2005
Apoptotic-cell removal is critical for development, tissue homeostasis, and resolution of inflammation. Although many candidate… (More)
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Highly Cited
2005
Highly Cited
2005
In probing adhesion and cell mechanics by atomic force microscopy (AFM), the mechanical properties of the membrane have an… (More)
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Review
2005
Review
2005
Signal regulatory proteins (SIRPs) constitute a family of transmembrane glycoproteins with extracellular Ig-like domains. Several… (More)
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Highly Cited
2002
Highly Cited
2002
Recent studies have demonstrated that CD47 plays an important role in regulating human neutrophil (PMN) chemotaxis. Two ligands… (More)
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Highly Cited
2002
Highly Cited
2002
Monocyte infiltration into inflamed tissue requires their initial arrest onto the endothelial cells (ECs), followed by firm… (More)
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Highly Cited
2000
Highly Cited
2000
The macrophage fusion receptor (MFR), also called P84/BIT/SIRPalpha/SHPS-1, is a transmembrane glycoprotein that belongs to the… (More)
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Highly Cited
1998
Highly Cited
1998
We had previously identified a macrophage surface protein whose expression is highly induced, transient, and specific, as it is… (More)
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