Skip to search formSkip to main contentSkip to account menu

SH2B3 wt Allele

Known as: IDDM20, LNK, SH2B Adaptor Protein 3 wt Allele 
Human SH2B3 wild-type allele is located in the vicinity of 12q24 and is approximately 46 kb in length. This allele, which encodes SH2B adapter… 
National Institutes of Health

Related topics

Related topics

9 relations
12q24Blood coagulationErythropoietin Signaling PathwayHematopoiesis

Broader (1)

SH2B3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
[Effect of Silencing and Overexpression of LNK Gene on STAT3 Expression in THP-1 Cells].
OBJECTIVE To investigate the effect of LNK gene silencing and overexpression on the expression of STAT3 gene in human monocytic… 
2018
2018
[Expression of LNK Genes in Patients with Acute Leukemia and Its Clinical Significance].
OBJECTIVE To investigate the expression of LNK gene in patients with acute leukemia (AL) and its correlation with the clinical… 
2018
2018
[Variation and Clinical Significance of LNK Gene in Essential Thrombocytosis].
OBJECTIVE To explore the mutation and single nucleotide polymorphism(SNP) of LNK gene in the patients with essential… 
2017
2017
[Variation of LNK Gene in Chronic Myeloid Leukemia].
OBJECTIVE To compare the mutation and single nucleotide polymorphism (SNP) of LNK gene between chronic myeloid leukemia(CML) and… 
2014
2014
LNK (SH2B3): paradoxical effects in ovarian cancer
LNK (SH2B3) is an adaptor protein studied extensively in normal and malignant hematopoietic cells. In these cells, it… 
Review
2014
Review
2014
Screening of JAK2 V617F and MPL W515 K/L negative essential thrombocythaemia patients for mutations in SESN2, DNAJC17, ST13, TOP1MT, and NTRK1
Essential thrombocythaemia (ET) is a myeloproliferative neoplasm characterized by a sustained elevation of the platelet count and… 
2014
2014
Clinical Significance of LNK (SH2B3) Expression in Pediatric B Cell Precursor Acute Lymphoblastic Leukemia
Background: In pediatric B cell precursor acute lymphoblastic leukemia (BCP-ALL), aberrant JAK-STAT signaling is one of the key… 
Review
2013
Review
2013
Role of the adaptor protein LNK in normal and malignant hematopoiesis
The signal transduction pathways, orchestrating the differentiation of hematopoietic stem and progenitor cells in response to… 
2012
2012
14-3-3 regulates the LNK / JAK 2 pathway in mouse hematopoietic stem and progenitor cells
Hematopoietic stem and progenitor cell (HSPC) functions are governed by intricate signaling networks. The tyrosine kinase JAK2… 
2011
2011
The carriage of the type 1 diabetes‐associated R262W variant of human LNK correlates with increased proliferation of peripheral blood monocytes in diabetic patients
Lavrikova EY, Nikitin AG, Kuraeva TL, Peterkova VA, Tsitlidze NM, Chistiakov DA, Nosikov VV. The carriage of the type 1 diabetes… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)