SH2 Domain-Containing Protein Tyrosine Phosphatases

Known as: SH2 Domain Containing Protein Tyrosine Phosphatases, SH2 Domain-Containing Protein Tyrosine Phosphatase, Protein-Tyrosine-Phosphatases, SH2 Domain-Containing 
A subcategory of protein tyrosine phosphatases that contain SH2 type SRC HOMOLOGY DOMAINS. Many of the proteins in this class are recruited to… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2018
0204019792018

Papers overview

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Highly Cited
2003
Highly Cited
2003
SAP (or SH2D1A), an adaptor-like molecule expressed in immune cells, is composed almost exclusively of a Src homology 2 (SH2… (More)
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2002
2002
The present study was intended to gain additional information on the growth regulation of prostate by somatostatin (SRIF) and the… (More)
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Highly Cited
1999
Highly Cited
1999
Leptin exerts its weight-reducing effects by binding to its receptor and activating signal transduction in hypothalamic neurons… (More)
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1998
1998
Receptor tyrosine phosphorylation is crucial for signal transduction by creating high affinity binding sites for Src homology 2… (More)
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1997
1997
The SH2 domain-containing inositol-polyphosphate 5-phosphatase, SHIP, associates with FcgammaRIIB and negatively regulates both B… (More)
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Highly Cited
1996
Highly Cited
1996
SHPTP1 (PTP1C, HCP, SHP) is an SH2 domain-containing tyrosine phosphatase expressed predominantly in hematopoietic cells. A… (More)
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Highly Cited
1996
Highly Cited
1996
THE protein Grb2 plays a central role in signalling by receptor protein-tyrosine kinases1,2, where its SH2 domain binds to the… (More)
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Highly Cited
1994
Highly Cited
1994
Src homology 2 (SH2) domains provide specificity to intracellular signaling by binding to specific phosphotyrosine (phospho-Tyr… (More)
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Highly Cited
1994
Highly Cited
1994
Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that participate in signaling by growth… (More)
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Highly Cited
1993
Highly Cited
1993
A Drosophila gene (drk) encodes a widely expressed protein with a single SH2 domain and two flanking SH3 domains, which is… (More)
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