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SGPP2 gene

Known as: SPP2, SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE 2, SGPP2 
This gene plays a role in sphingosine-1-phosphate catabolism.
National Institutes of Health

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Related topics

4 relations
DephosphorylationHydrolysisSGPP2 protein, human

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SGPP2 wt Allele

Papers overview

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2016
2016
Sphingosine‐1‐phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans
The bioactive sphingolipid sphingosine‐1‐phosphate (S1P) and the kinase that produces it have been implicated in inflammatory… Expand
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2015
2015
Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD)
Introduction We previously reported that alveolar macrophages from patients with chronic obstructive pulmonary disease (COPD) are… Expand
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2015
2015
The relationship between the high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P) and coronary in-stent restenosis.
BACKGROUND High-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P) contributed to several beneficial effects in… Expand
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2015
2015
Tumor suppressor microRNA-31 inhibits gastric carcinogenesis by targeting Smad4 and SGPP2
To investigate the function of microRNA-31 (miR-31) in the pathogenesis of gastric cancer (GC) and to explore the possible… Expand
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2015
2015
SPP2 Mutations Cause Autosomal Dominant Retinitis Pigmentosa
Retinitis pigmentosa (RP) shows progressive loss of photoreceptors involved with heterogeneous genetic background. Here, by exome… Expand
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Highly Cited
2013
Highly Cited
2013
A Metabolic Shift Favoring Sphingosine 1-Phosphate at the Expense of Ceramide Controls Glioblastoma Angiogenesis*
Background: The sphingolipid metabolite sphingosine 1-phosphate (S1P) is a potent angiogenic factor. Results: S1P content is 9… Expand
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2013
2013
Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function
BackgroundVitamin D is associated with lung health in epidemiologic studies, but mechanisms mediating observed associations are… Expand
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2012
2012
Use of germline polymorphisms in predicting concurrent chemoradiotherapy response in esophageal cancer.
PURPOSE To identify germline polymorphisms to predict concurrent chemoradiation therapy (CCRT) response in esophageal cancer… Expand
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2010
2010
Downstream Gene Activation of the Receptor ALX by the Agonist Annexin A1
Background Our understanding of pro-resolution factors in determining the outcome of inflammation has recently gained ground, yet… Expand
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Highly Cited
2005
Highly Cited
2005
Microarray analysis of differential gene expression in temporomandibular joint condylar cartilage after experimentally induced osteoarthritis.
OBJECTIVE To identify the gene expression profile of mandibular condylar cartilage after experimentally induced osteoarthritis… Expand
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