SGI-1027

 

Topic mentions per year

Topic mentions per year

2009-2017
012320092017

Papers overview

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2016
2016
Müller glia (MG) is the most abundant glial type in the vertebrate retina. Among its many functions, it is capable of responding… (More)
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2015
2015
Among the epigenetic marks, DNA methylation is one of the most studied. It is highly deregulated in numerous diseases, including… (More)
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2014
2014
Quinoline derivative SGI-1027 (N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide) was first… (More)
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2014
2014
DNA methylation is an epigenetic modification essential for normal development and maintenance of somatic biological functions… (More)
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2014
2014
After extensive research on radiochemotherapy, 5-year survival rates of children with high risk neuroblastoma still do not exceed… (More)
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2013
2013
The known DNMT inhibitor SGI-1027 4 has been synthesized using as key steps Pd-catalyzed Ar-N bond formation reactions performed… (More)
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2013
2013
DNA methylation is an epigenetic modification that regulates gene expression by DNA methyltransferases (DNMTs). Inhibition of… (More)
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2013
2013
A series of 4-anilinoquinoline derivatives related to the known inhibitor SGI-1027, containing side chains of varying pK(a), were… (More)
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2012
2012
DNA methyltransferases (DNMTs) are emerging targets for the treatment of cancer and other diseases. The quinolone-based compound… (More)
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2009
2009
Reactivation of silenced tumor suppressor genes by 5-azacytidine (Vidaza) and its congener 5-aza-2'-deoxycytidine (decitabine… (More)
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