SF3B1 gene

Known as: Splicing Factor 3b, Subunit 1, 155kDa Gene, SPLICING FACTOR 3B, SUBUNIT 1, Prp10 
This gene is involved in mRNA splicing.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
UNLABELLED Uveal melanoma, the most common eye malignancy, causes severe visual morbidity and is fatal in approximately 50% of… (More)
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Highly Cited
2013
Highly Cited
2013
Uveal melanoma is the most common primary cancer of the eye and often results in fatal metastasis. Here, we describe mutations… (More)
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Highly Cited
2013
Highly Cited
2013
Gene expression profiles and chromosome 3 copy number divide uveal melanomas into two distinct classes correlating with prognosis… (More)
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Highly Cited
2012
Highly Cited
2012
Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed exome sequencing and copy number… (More)
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Highly Cited
2011
Highly Cited
2011
Here we perform whole-exome sequencing of samples from 105 individuals with chronic lymphocytic leukemia (CLL), the most frequent… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND The somatic genetic basis of chronic lymphocytic leukemia, a common and clinically heterogeneous leukemia occurring in… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Myelodysplastic syndromes are a diverse and common group of chronic hematologic cancers. The identification of new… (More)
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Highly Cited
2011
Highly Cited
2011
In a previous study, we identified somatic mutations of SF3B1, a gene encoding a core component of RNA splicing machinery, in… (More)
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Highly Cited
2011
Highly Cited
2011
Myelodysplastic syndromes and related disorders (myelodysplasia) are a heterogeneous group of myeloid neoplasms showing… (More)
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Highly Cited
2011
Highly Cited
2011
The genetic lesions identified in chronic lymphocytic leukemia (CLL) do not entirely recapitulate the disease pathogenesis and… (More)
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