SETD2 gene

Known as: KMT3A, KIAA1732, HYPB 
This gene is involved in epigenetic control of gene expression.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
051019932017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Recurrent mutations affecting the histone H3.3 residues Lys27 or indirectly Lys36 are frequent drivers of pediatric high-grade… (More)
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Highly Cited
2011
Highly Cited
2011
Several lines of recent evidence support a role for chromatin in splicing regulation. Here, we show that splicing can also… (More)
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Highly Cited
2010
Highly Cited
2010
Sporadic clear cell renal cell carcinoma (cRCC) is genetically characterized by the recurrent loss of the short arm of chromosome… (More)
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Highly Cited
2008
Highly Cited
2008
Understanding the function of histone modifications across inducible genes in mammalian cells requires quantitative, comparative… (More)
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Highly Cited
2008
Highly Cited
2008
Many steps in gene expression and mRNA biosynthesis are coupled to transcription elongation and organized through the C-terminal… (More)
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Highly Cited
2005
Highly Cited
2005
Yeast Rpd3 histone deacetylase plays an important role at actively transcribed genes. We characterized two distinct Rpd3… (More)
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Highly Cited
2005
Highly Cited
2005
Histone methylation and the enzymes that mediate it are important regulators of chromatin structure and gene transcription. In… (More)
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Highly Cited
2003
Highly Cited
2003
Set2 methylates Lys36 of histone H3. We show here that yeast Set2 copurifies with RNA polymerase II (RNAPII). Chromatin… (More)
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Highly Cited
2003
Highly Cited
2003
Histone methylation is now realized to be a pivotal regulator of gene transcription. Although recent studies have shed light on a… (More)
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Highly Cited
2003
Highly Cited
2003
Existing evidence indicates that SET2, the histone 3 lysine 36 methyltransferase of Saccharomyces cerevisiae, is a… (More)
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